azelaic acid/neoplasms

Le lien est enregistré dans le presse-papiers

Choisissez le type de tri

Page 1 de 17 résultats

Crystal structure of a 1:1 co-crystal of the anti-cancer drug gefitinib with azelaic acid

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

In the title co-crystal, C₂₂H₂₄ClFN₄O₃·C₉H₁₆O₄, gefitinib (GTB; systematic name: quinazolin-4-amine) co-crystallizes with azelaic acid (AA; systematic name: nona-nedioic acid). The co-crystal has the monoclinic

Gene expression profile of high-fat diet-fed C57BL/6J mice: in search of potential role of azelaic acid.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

High-fat diet (HFD) elevates circulatory fatty acids and influences glucose and fat metabolism. Azelaic acid (AzA), a naturally occurring α,ω-dicarboxylic acid in wheat, rye, barley, oat seeds and sorghum, has been reported to exert antidiabetic effects in HFD-induced type 2 diabetes mellitus (T2DM)

An evaluation of the effectiveness of azelaic acid as a depigmenting and chemotherapeutic agent.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

In the past five years, it has been reported that certain dicarboxylic acids (C8-C13) and azelaic acid (C9) (AZA), in particular, have a remarkable effect in the management of lentigo maligna, human malignant melanoma, and certain disorders of hyperpigmentation. Preclinical trials, therefore, were

Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Acute myeloid leukemia (AML) is a common type of hematological malignancy that can progress rapidly. AML has a poor prognosis and a high incidence of relapse due to therapeutic resistance. Azelaic acid (AZA), a small molecular compound is known to exhibit antitumor effect on various tumor cells.

Azelaic Acid Exerts Antileukemic Activity in Acute Myeloid Leukemia.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Acute myeloid leukemia (AML) is an acute leukemia common in most adults; its prevalence intensifies with age. The overall survival of AML is very poor because of therapeutic resistance. Azelaic acid (AZA) is non-toxic, non-teratogenic, and non-mutagenic and its antitumor effect on various tumor

Metabolomic analysis of lung cancer patients with chronic obstructive pulmonary disease using gas chromatography-mass spectrometry

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Chronic obstructive pulmonary disease (COPD), characterized by intermittent exacerbations and clinical subphenotypes like emphysema and chronic bronchitis, poses a significant risk of lung cancer (LC) development. Metabolomic studies of COPD are scarce, and those of LC patients with COPD

Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Azelaic bishydroxamic acid (ABHA), a potent differentiating agent for lymphoid cells, was selectively toxic for 5 human tumor cell lines and transformed human melanocytes and keratinocytes (dose for 37% survival, D37, 30-100 microg/mL) compared with normal cells (melanocytes, fibroblasts; D37 > 300

Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARgamma activation.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Azelaic acid (AzA), a nine-carbon dicarboxylic acid, is an agent for the topical treatment of acne. It has also been shown to be effective in rosacea; however, the mechanism of action has not been clarified. Because inflammation is a common feature of both conditions, we investigated the effects of

Azelaic acid: potential as a general antitumoural agent.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Azelaic acid is a naturally occurring straight-chained 9-carbon atom dicarboxylic acid which is non-toxic, non-teratogenic, and non-mutagenic. Its antiproliferative and cytotoxic effect on a variety of tumoural cell lines in culture, due to inhibition of mitochondrial oxidoreductases of the

Total synthesis of (-)-minquartynoic acid: an anti-cancer, anti-HIV natural product.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

[structure: see text] The tetraacetylenic compound, (S)-minquartynoic acid (1), is synthesized in seven linear steps and 17% overall yield from commercially available azelaic acid monomethyl ester. The key step is a one-pot three-component Cadiot-Chodkiewicz reaction to construct the tetrayne unit

Prosthechea karwinskii, an orchid used as traditional medicine, exerts anti-inflammatory activity and inhibits ROS.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

Prosthechea karwinskii (Mart.) J.M.H. Shaw is a Mexican orchid used in traditional medicine by some indigenous communities to treat issues related to inflammation (cough, wounds, burns, and diabetes). Pharmacological research of this orchid could validate its therapeutic uses and

The mechanism of action and clinical benefits of soy for the treatment of hyperpigmentation.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

BACKGROUND Hyperpigmentation disorders are common and diverse conditions that may require treatment for medical and/or cosmetic reasons. Hyperpigmented lesions can reduce patients' quality of life, self-perception, and social and vocational functioning. The most commonly used treatments for

A lifetime of healthy skin: implications for women.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

During her lifetime, a woman faces the possibility of seeking dermatological assistance for a myriad of conditions, including acne, rosacea, striae, photodamage, and skin cancers. It is important for clinicians and patients to be aware of the symptoms of these conditions as well as the most

The cytokine hypothesis of depression: inflammation, oxidative & nitrosative stress (IO&NS) and leaky gut as new targets for adjunctive treatments in depression.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

This paper hypothesizes that inflammatory, oxidative and nitrosative (IO&NS) pathways, and an increased translocation of LPS from gram-negative bacteria are causally related to depression following external (psychological) and internal (organic) stressors and that IO&NS pathways are novel targets

Mono- and digalactosyldiacylglycerol lipids function nonredundantly to regulate systemic acquired resistance in plants.

Seuls les utilisateurs enregistrés peuvent traduire des articles

Se connecter S'inscrire

The plant galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) have been linked to the anti-inflammatory and cancer benefits of a green leafy vegetable diet in humans due to their ability to regulate the levels of free radicals like nitric oxide (NO). Here, we show

Rejoignez notre
page facebook

Herbal & Natural Medicine

La base de données d'herbes médicinales la plus complète soutenue par la science

Fonctionne en 55 langues
Cures à base de plantes soutenues par la science
Reconnaissance des herbes par image
Carte GPS interactive - étiquetez les herbes sur place (à venir)
Lisez les publications scientifiques liées à votre recherche
Rechercher les herbes médicinales par leurs effets
Organisez vos intérêts et restez à jour avec les nouvelles recherches, essais cliniques et brevets

Tapez un symptôme ou une maladie et lisez des informations sur les herbes qui pourraient aider, tapez une herbe et voyez les maladies et symptômes contre lesquels elle est utilisée.
* Toutes les informations sont basées sur des recherches scientifiques publiées