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benzothiazole/neoplasms
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Benzothiazole PI3 kinase modulators for cancer treatment
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FIELD OF THE INVENTION
The invention generally relates to the field of pharmaceutical agents and, specifically to compounds, intermediates and pharmaceutical compositions capable of modulating Phosphoinositide 3-kinase (PI3K) activity and useful for treating PI3K mediated diseases, such as
Benzothiazole derivatives and a use thereof for the treatment of cancer
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BACKGROUND
1. Field
One or more embodiments of the present invention relate to novel benzothiazole derivative compounds effective for cancer treatment, and more particularly, to a benzothiazole derivative compound, a use of the benzothiazole derivative compound for cancer treatment, and a use of the
Benzothiazole derivatives and a use thereof for the treatment of cancer
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BACKGROUND
1. Field
One or more embodiments of the present invention relate to novel benzothiazole derivative compounds effective for cancer treatment, and more particularly, to a benzothiazole derivative compound, a use of the benzothiazole derivative compound for cancer treatment, and a use of the
6-O-substituted benzoxazole and benzothiazole compounds and methods of inhibiting CSF-1R signaling
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to 6-O-substituted benzoxazole and benzothiazole compounds, their tautomers, stereoisomers, solvates, oxides, esters, metabolites, and prodrugs, and to the pharmaceutically acceptable salts thereof. This invention
Methods and compositions for selective and targeted cancer therapy
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FIELD
Presented herein are methods and compositions for selective and targeted cancer therapy, in particular N-acylated amino heterocycles, heterocyclic carboxamides, oxalamides, N-acyl ureas, and chromones and their use in selectively treating certain cancers.
BACKGROUND
Cancer therapies aim to
2-(3-Trimethylsilylpropyl)benzothiazole
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BACKGROUND OF THE INVENTION
The present invention relates to a novel organosilicon compound derived from benzothiazole and a method for the preparation thereof. The invention further relates to a method for preventing growth of tumor cells by medicating a patient with the above organosilicon
2-phenyl benzothiazole linked imidazole compounds as potential anticancer agents and process for the preparation thereof
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FIELD OF THE INVENTION
The present invention relates to 2-phenyl benzothiazole linked imidazole compounds of general formula A as potential anticancer agents and a process for the preparation thereof
##STR00003## wherein
##STR00004##
The structural formula of the representative group of 2-phenyl
2-anilino nicotinyl linked 2-amino benzothiazole conjugates and process for the preparation thereof
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FIELD OF THE INVENTION
The present invention relates to 2-anilino nicotinyl linked 2-amino benzothiazole of general formula A as potential anticancer agents and apoptosis inducers.
##STR00002## wherein R.sup.1.dbd.H or Cl; R.sup.2.dbd.H, OCH.sub.3 or F; R.sup.3.dbd.H, OCH.sub.3, F or Cl;
Benzothiazole derivatives
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BACKGROUND OF THE INVENTION
The present invention is directed to benzothiazole derivatives of formula (I), as defined below, uses and pharmaceutical compositions thereof.
There are at least 400 enzymes identified as protein kinases. These enzymes catalyze the phosphorylation of target protein
Synthesis of 2-(4-aminophenyl) benzothiazole derivatives and use thereof
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FIELD OF THE INVENTION
The present invention relates to a method of preparing a compound of 2-(4-aminophenyl)benzothiazoles. The present invention also relates to a method of providing photodynamic therapy to a patient having at least one tumor by administering the compound in a pharmaceutically
Process for the preparation of imidazo[2,1-B][1,3]benzothiazole derivatives
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II. FIELD
Provided herein are processes for the preparation of N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[- 2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt, solvate, hydrate, or polymorph thereof.
Benzothiazole amphiphiles
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BACKGROUND
Dendritic complexity, synaptogenesis, and overall proper development and function of neurons are regulated by growth factors such as brain derived neurotrophic factor (BDNF). Estrogen (specifically, estradiol) is an example of a small molecule that is known to promote dendritic spine
Synthesis of 2-(4-aminophenyl)benzothiazole derivatives and use thereof
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FIELD OF THE INVENTION
The present invention relates to a method of preparing a compound of 2-(4-aminophenyl)benzothiazoles. The present invention also relates to a method of providing photodynamic therapy to a patient having at least one tumor by administering the compound in a pharmaceutically
Benzothiazole or benzoxazole compounds as sumo activators
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TECHNICAL FIELD
The present application relates to SUMO activators, which can enhance SUMOylation of SERCA2a, which are useful in the treatment of heart failure, cardiovascular diseases, cancer, neurodegenerative disorders, viral infection, bacterial infection, liver disease, inflammation, and other
Benzothiazole or benzoxazole compounds as SUMO activators
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TECHNICAL FIELD
The present application relates to SUMO activators, which can enhance SUMOylation of SERCA2a, which are useful in the treatment of heart failure, cardiovascular diseases, cancer, neurodegenerative disorders, viral infection, bacterial infection, liver disease, inflammation, and other
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