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colorectal neoplasms/œdème

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Development and Validation of an Artificial Intelligence-assisted Strategy Selection System for Colonoscopy Cleaning

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Colorectal disease as a common human disease seriously affects the health of human life. With the aging of the population, the change of diet structure and the aggravation of environmental pollution, the incidence of colorectal diseases, such as colon cancer, Colon Polyp and inflammatory bowel

Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia

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- Preeclampsia (PE) is a diverse multisystem syndrome defined as a new onset of hypertension along with evidence of significant multiorgan dysfunction in previously normotensive women 20 weeks of gestation (1) - The incidence of PE is around 2 - 8 % of pregnancies and it causes about 50,000 deaths

Glucocorticoids, Immunotherapy and Radiosurgery for Brain Metastases

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Restrictive or Doppler-guided Fluid Treatment in Colorectal Surgery

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Background Hypovolemia can cause postoperative complications, circulatory collapse and death, regardless if the cause is blood loss or loss of other fluids. Therefore, doctors are giving fluid intravenously to patients undergoing surgery, and often in an amount larger than the measured losses.

Intravitreal Injections of Ziv-aflibercept for Macular Diseases

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Twenty consecutive patients with DME, wet-AMD and macular edema secondary to vein occlusions will be enrolled. A complete examination including full-field ERG, visual acuity, central retinal thickness (CRT) and evaluation of systemic and ocular complications will be performed before and 24 weeks

Ziv-aflibercept in Eyes With Retinal Diseases and Poor Vision-phase I

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Protocol Inject 0.05 ml of zaltrap coumpounded in a sterile way into the vitreous of blind eyes (vision less than 20/100) with various diseases of the retina that require antiVEGF therapy after patient consent. Vision will be monitored 15 minutes, 1 day and 1 week after injection. SD-OCT will be

Italian Study Group on Complicated Diverticulosis

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A Phase I Study of ABT-510 in Combination With Bevacizumab in Advanced Solid Tumors

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ABT-510: In the early 1990s, thrombospondin (TSP-1) was first recognized as an endogenously produced inhibitor of angiogenesis. Since then, thrombospondin has been shown to inhibit neovascularization and tumorigenesis in numerous mouse models. Its anti- angiogenesis properties have been localized to

Unilateral Bevacizumab for Bilateral Diabetic Macular Edema

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Introduction: The endothelial growth factor (VEGF), was identified for the first time in the liquid of ascitis in Guinean pigs (6,7). It is a dimeric glycoprotein, naturally expressed in epithelial and tumor cells (1). It's over expression during retinal hypoxia (9), has been implied in the genesis
There is an unmet clinical need for effective therapy of breast cancer that has metastasized to the brain. In this scenario, median survival is around 12 months using currently available therapeutic interventions. The majority of chemotherapy-based clinical trials have considered the presence of

A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin)

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Diabetic retinopathy is a major cause of visual impairment in the United States. Diabetic macular edema (DME) is a manifestation of diabetic retinopathy that produces loss of central vision. Data from the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR) estimate that after 15 years of
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