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coronary artery disease/crise épileptique
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Use of isatin derivatives as ion channel activating agents
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TECHNICAL FIELD
The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SK.sub.Ca and IK.sub.Ca channels. In further aspects, the present invention relates to the
Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a national phase of International Application No. PCT/US2014/027450 filed on Mar. 14, 2014, which claims the benefit of U.S. Provisional Application No. 61/785,478 filed on Mar. 14, 2013, each of which are incorporated herein by reference
Potassium channel modulating agents and their medical use
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This application is the national phase of PCT application PCT/EP2006/060643 filed on Mar. 13, 2006 and claims priority under 35 U.S.C. 119(e) on Provisional Application No(s). 60/661,149 filed on Mar. 14, 2005 and under 35 U.S.C. 119(a) on patent application No(s). PA 2005 00366 filed in Denamark on
Indazolyl derivatives useful as potassium channel modulating agents
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TECHNICAL FIELD
This invention relates to novel indazolyl derivatives useful as potassium channel modulating agents, and their use in the preparation of pharmaceutical compositions.
Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases
Pyridone substituted benzothiazole derivatives
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BACKGROUND OF THE INVENTION
The present invention generally relates to pyridone substituted benzothiazole compounds that are adenosine receptor ligands. Specifically, the compounds of the present invention have a good affinity to the A.sub.2A -receptor and a high selectivity to the A.sub.1 - and
Benzathiazol-acetamides
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BACKGROUND OF THE INVENTION
Adenosine modulates a wide range of physiological functions by interacting with specific cell surface receptors. The potential of adenosine receptors as drug targets was first reviewed in 1982. Adenosine is related both structurally and metabolically to the bioactive
Benzothiazole derivatives
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BACKGROUND OF THE INVENTION
Adenosine modulates a wide range of physiological functions by interacting with specific cell surface receptors. The potential of adenosine receptors as drug targets was first reviewed in 1982. Adenosine is related both structurally and metabolically to the bioactive
Isoquinoline derivatives or salts thereof
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TECHNICAL FIELD
The present invention relates to drugs, particularly to novel isoquinoline derivatives or salts having a I.sub.f current inhibitory effect without serious side effects such as convulsion and also to drugs, particularly cardiac rate lowering agents containing these compounds as the
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