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costus/hypersensibilité
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Allergic contact dermatitis to costus: removal of haptens with polymers.
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Costus oil, an iol isolated from a Composite, Saussurea lappa C., used in perfumery, is responsible of numerous cases of allergic contact dermatitis (ACD). The haptens incriminated are sesquiterpene lactones, costunolide and dehydrocostuslactone. These lactones can be removed from the oil by using a
Anti-allergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments.
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BACKGROUND
Saussurea costus (Falc.) Lipsch. root has been used in Asian traditional medicine for the treatment of asthma, rheumatism, and other conditions. S. costus extracts were shown to alleviate house dust mite-induced atopic-like dermatitis in Nc/Nga mice; besides, sesquiterpene lactones were
Contact hypersensitivity to a perfume material, Costus Absolute. The role of sesquiterpene lactones.
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[Newly recognized primary sensitizers, methyl heptine carbonate and costus root oil to evaluate cutaneous delayed hypersensitivity on various chest diseases (author's transl)].
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[Cutaneous delayed hypersensitivity to costus root oil in lung cancer].
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Costus root oil is a new primary sensitizer for examining the delayed, cell-mediated immune system. Ninety-nine patients with lung cancer were tested for skin reactions to costus root oil. The incidence of positive reactions to costus root oil decreased with the progress of lung cancer. The
[Skin sensitization of costus root oil and peripheral lymphocyte count in gastric and colon cancers].
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Costus root oil is a new primary sensitizer to examine the delayed, cell-mediated immune system. The peripheral blood lymphocyte count has been measured in 68 cases of carcinoma of the stomach and colon. The count has been correlated with the stage of tumor spread and the patient's delayed
[Costus root oil test in cancer patients; correlation with tumor stage].
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Delayed hypersensitivity skin responses to costus root oil were measured in patients with colon, stomach, breast and lung cancer and in healthy controls. Cancer patients were staged according to tumor spread. Differences were demonstrated between cancer patients and controls. Patients with localized
[Effect of costus root oil in murine tumors].
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Costus root oil is a new primary sensitizer for examination of the delayed cell-mediated immune system. Histologic findings of skin producing a positive reaction to costus root oil show accumulation of lymphoid cells. If the delayed hypersensitivity reaction caused by costus root oil were to be used
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