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dermatitis/phosphatase
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[Differential diagnosis of allergic and non-allergic dermatitis by measuring the levels of acid phosphatase in neutrophils and peripheral blood lymphocytes].
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Using the cytoenzymatic method acid phosphatase was determined in peripheral blood neutrophils and lymphocytes in 25 patients with allergic eczema, 31 patients with eczema due to irritants and 18 clinically healthy subjects. In patients with allergic eczema the percent of neutrophils and lymphocytes
The phosphatase regulator NIPP1 restrains chemokine-driven skin inflammation.
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NIPP1 is a ubiquitously expressed nuclear protein that regulates functions of protein Ser/Thr phosphatase-1 in cell proliferation and lineage specification. The role of NIPP1 in tissue homeostasis is not fully understood. Here we show that the selective deletion of NIPP1 in mouse epidermis resulted
Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis.
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BACKGROUND
Atopic dermatitis (AD) and psoriasis are the 2 most common chronic inflammatory skin diseases. There is an unmet medical need to overcome limitations for transcutaneous drug development posed by the skin barrier.
OBJECTIVE
We aimed to identify a novel transdermal delivery peptide and to
[The alkaline phosphatase activity of the blood serum as a factor reflecting the chronic inflammatory process in the skin in generalized forms of psoriasis, neurodermatitis, eczema and trophic ulcers].
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Blood serum alkaline phosphatase (AP) level was found elevated in the patients suffering from eczema, neurodermatitis, eczema with large skin sites involved, and in those with trophic ulcers of various origins, as against normal subjects and reference patients with sarcoidosis and Kaposi's sarcoma.
Glutamine suppresses DNFB-induced contact dermatitis by deactivating p38 mitogen-activated protein kinase via induction of MAPK phosphatase-1.
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L-glutamine (Gln) is a nonessential amino acid that is the most abundant amino acid in plasma. Gln has been reported to have an anti-inflammatory activity that involves deactivation of mitogen-activated protein kinases (MAPKs) in a MAPK phosphatase (MKP)-1-dependent manner. This study investigated
The immune checkpoint receptor associated phosphatases SHP-1 and SHP-2 are not required for γδT17 cell development, activation or skin inflammation.
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Interleukin(IL)-17 producing gamma delta (γδT17) cells are innate lymphocytes critical for anti-bacterial protection at barrier surfaces such as the skin but also highly pathogenic during inflammation. It is therefore important to understand the cellular and molecular mechanisms that could
EXPERIMENTAL ECZEMA. 21. ALKALINE PHOSPHATASE IN ECZEMA OF THE GUINEA PIG TREATED WITH DINITROCHLOROBENZENE.
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[Proof of alkaline phosphatase in the human epidermis in an acute exacerbation of eczema].
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Extreme rises in serum alkaline phosphatase in children with atopic dermatitis after intervention treatment with cyclosporin A.
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Leukocytosis associated with low leukocyte alkaline phosphatase score following intravenous steroid therapy for atopic dermatitis.
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[Activity of alkaline and acid phosphatases in eczema].
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Identification of IgE-reactive proteins in patients with wheat protein contact dermatitis.
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BACKGROUND
Wheat protein and its derivatives can cause protein contact dermatitis (PCD), which mainly occurs in bakers. Few studies have attempted to identify the allergens responsible for wheat PCD.
OBJECTIVE
The aim of this study was to identify allergenic wheat proteins in patients with wheat
Vitamin D deficiency rickets in an adolescent with severe atopic dermatitis.
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Atopic dermatitis (AD) affects 10% to 20% of children worldwide. Its severity may be inversely correlated with 25-hydroxyvitamin D (25OHD) levels. Although low levels of vitamin D (VD) can cause rickets in infants, VD deficiency rickets is an unusual presentation in teenagers. We report the case of
[Ultrastructure of the epidermis in seborrhoic dermatitis (author's transl)].
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Electronmicroscopical investigation on 12 cutaneous biopsies of different localisation showed that the seborrhoic dermatitis is not comparable to a psoriatic tissue-reaction. Both, the cyto-morphological feature and the demonstrated localisation of the acid phosphatase are distinctly different from
Superficial necrolytic dermatitis (necrolytic migratory erythema) in dogs.
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Twenty-two dogs with superficial necrolytic dermatitis were evaluated prospectively, twenty-one of which had characteristic crusting lesions of the paw pads. Histologically, epidermal lesions included parakeratosis and laminar intracellular edema. The plasma amino acid concentrations of eight dogs
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