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dermatitis/protease
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Topical and orally administered protease inhibitors and bacterial vectors for the treatment of disorders and methods of treatment
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CROSS REFERENCE TO RELATED APPLICATIONS
The present application is a non-provisional of U.S. Provisional patent application 61/939,992, filed Feb. 14, 2014, and U.S. Provisional patent application 61/939,740, filed Feb. 14, 2014, and of U.S. Provisional patent application 61/940,019, filed Feb. 14,
Protease inhibitors in absorbent articles
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BACKGROUND OF THE INVENTION
The invention relates to absorbent articles such as diapers, training pants, adult incontinence briefs, feminine hygiene products, and the like. In particular, the absorbent articles of the invention contain fecal protease inhibitors and are useful for the prevention and
Disposable premoistened wipe containing an antimicrobial protease inhibitor
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FIELD OF THE INVENTION
The present invention relates to disposable premoistened wipes, and more particularly to disposable premoistened wipes which include an antimicrobial protease inhibitor effective at inhibiting deleterious fecal microorganisms and inhibiting protease enzymes.
BACKGROUND OF THE
Prevention and treatment of itch with cysteine protease inhibition
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BACKGROUND OF INVENTION
Itch, or pruritus, is the unpleasant sensation that leads to a desire to scratch and is a common and distressing symptom in a variety of conditions and diseases. Itch also typically occurs in peripheral diseases such as allergic conjunctivitis, allergic rhinitis, hemorrhoids,
Combination therapy with IgA1 proteases
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BACKGROUND
Immunoglobulin A1 (IgA1) deposition in human tissues and organs is a characteristic of many human diseases including IgA nephropathy, Dermatitis herpetiformis (DH), and Henoch-Schoenlein purpura (HS). IgA1 deposition is responsible for a variety of clinical manifestations such as renal
Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
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BACKGROUND OF THE INVENTION
Field of the Invention
This invention is generally in the field of therapeutic delivery systems, including genetically engineered probiotic and attenuated bacteria compositions and methods for providing co-expression of protease inhibitors with plasmids, phage, phagmids
Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
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CROSS REFERENCE TO RELATED APPLICATION
The present application is a non-provisional of U.S. Provisional Application No. 61/764,577, filed Feb. 14, 2013, the entirety of which is expressly incorporated herein by reference.
1. BACKGROUND OF THE INVENTION
1.1. Field of the Invention
This invention is
Diaper dermatitis preventative medication and a method for making and using same
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a composition for the prophylaxis and/or treatment of diaper dermatitis or similar dermal irritation and methods for making and using the composition.
More particularly, the present invention relates to a
Diaper dermatitis preventative medication and a method for making and using same
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a composition for the prophylaxis and/or treatment of diaper dermatitis or similar dermal irritation and methods for making and using the composition.
More particularly, the present invention relates to a
Combination of acid protease enzymes and acidic buffers and uses thereof
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1. FIELD OF THE INVENTION
This invention relates to novel compositions comprising one or more of an acid protease enzyme and an acidic buffer, the acidic buffer comprising an acid and a pharmaceutically or cosmetically acceptable carrier, useful for treating or preventing abnormal skin conditions,
Combination of acid protease enzymes and acidic buffers and uses thereof
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FIELD OF THE INVENTION
This invention relates to novel compositions comprising one or more of an acid protease enzyme and an acidic buffer, the acidic buffer comprising an acidic buffering component that can reversibly disassociate hydrogen ions and has buffering capacity at pH values below that of
Inhibitors of protease-activated receptor-2
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FIELD
The present application relates to the treatment or prevention of conditions or disorders related to pain, musculoskeletal inflammation such as osteoarthritis, neuroinflammatory disorders, airway inflammation, itch, dermatitis, colitis and related conditions with substituted imidazoles
Serine protease inhibitors-N-substituted derivatives
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors-keto and di-keto containing ring systems
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which include elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Val-pro containing .alpha.-keto oxadiazoles as serine protease inhibitors
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102 (chymotrypsin numbering system). Human
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