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diabetes complications/obésité
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Use of diazoxide for the treatment of metabolic syndrome and diabetes complications
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FIELD AND BACKGROUND OF THE INVENTION
The present invention relates to a novel treatment for metabolic syndrome and resulting complications, such as obesity, hypertension, hyperlipidemia, hyperinsulinemia and impaired glucose tolerance. In addition, it concerns the use of diazoxide for the treatment
Pyrimidine derivatives as GPCR modulators for use in the treatment of obesity and diabetes
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FIELD OF THE INVENTION
The present invention relates to Pyrimidine Derivatives, compositions comprising a Pyrimidine Derivative, and methods of using the Pyrimidine Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a metabolic disorder, a cardiovascular disease or a
Pharmaceutical composition comprising N-aryl N' morpholino/piperidino thiocarbamide derivatives for treating type II diabetes
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims benefit under 35 U.S.C. .sctn.119 from Korean Patent Application No. 2004-112874, filed on Dec. 27, 2004, the entire content of which is incorporated herein by reference.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
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TECHNICAL FIELD
The present invention relates to glucopyopyranosyloxypyrazole derivatives, pharmaceutically acceptable salts thereof or prodrugs thereof which are useful as medicaments, production intermediates thereof and pharmaceutical uses thereof.
More particularly, the present invention relates
Oxotetrahydrofuran-2-yl-benzimidazole derivative
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TECHNICAL FIELD
The present invention relates to glucokinase activators comprising an oxotetrahydrofuran-2-yl-benzimidazoles as an active ingredient thereof. The present invention further relates to a novel oxotetrahydrofuran-2-yl-benzimidazole derivative.
BACKGROUND ART
Glucokinase (gk) (atp:
Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
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TECHNICAL FIELD
The present invention relates to glucopyranosyloxybenzylbenzene derivatives and pharmaceutically acceptable salts thereof which are useful as medicaments and pharmaceutical uses thereof.
More particularly, the present invention relates to glucopyranosyloxybenzylbenzene derivatives
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
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TECHNICAL FIELD
The present invention relates to glucopyranosyloxypyrazole derivatives, pharmaceutically acceptable salts thereof or prodrugs thereof which are useful as medicaments, production intermediates thereof and pharmaceutical uses thereof.
More particularly, the present invention relates to
Glucopyranosyloxypyrazole derivatives and medicinal use thereof
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This is a 371 of PCT/JP02/01707, and claims benefit from Japanese Applications 51278/2001 filed Feb. 26, 2001 and 52903/2001 filed Feb. 27, 2001, each of which is incorporated herein by reference.
TECHNICAL FIELD
The present invention relates to glucopyranosyloxypyrazole derivatives,
Glucopyranosyloxypyrazole derivative medicinal composition containing the same medicinal use thereof and intermediate therefor
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TECHNICAL FIELD
The present invention relates to glucopyranosyloxypyrazole derivatives, pharmaceutically acceptable salts thereof or prodrugs thereof which are useful as medicaments, pharmaceutical compositions containing the same, pharmaceutical uses thereof and production intermediates
Acetyl pyrrolidinyl indole derivative
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TECHNICAL FIELD
The present invention relates to a glucokinase activator comprising an acetyl pyrrolidinyl indole derivative as the active ingredient thereof. Further, it relates to a novel acetyl pyrrolidinyl indole derivatives.
BACKGROUND ART
Glucokinase (GK) (ATP: D-hexose 6-phosphotransferaze,
Dipeptidyl peptidase IV inhibitors and processes for their preparation and pharmaceutical compositions containing them
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FIELD OF INVENTION
The present invention relates to novel compounds represented by formula I, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their bioisosters, their diastereomers, their polymorphs, their pharmaceutically acceptable salts, solvates and
Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
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FIELD OF THE INVENTION
The present invention relates to certain heterocyclic compounds useful as diacylglycerol acyltransferase ("DGAT") inhibitors, especially diacylglycerol acyltransferase 1 ("DGAT1") inhibitors, pharmaceutical compositions containing the compounds, and methods of treatment using
Benzene compounds
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to benzene compounds, and more particularly, to novel benzene compounds having inhibition activity on acetyl CoA carboxylase ("ACC" hereinafter).
2. Discussion of the Background
It has become clear in recent years
Benzimidazole derivatives, their preparation and their therapeutic use
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BACKGROUND TO THE INVENTION
The present invention relates to a series of benzimidazole compounds having hypoglycemic, anti-diabetic, anti-cataract and 5-lipoxygenase inhibitory activities, the ability to inhibit the formation of lipid peroxide and related activities, as described in more detail
Bicyclic compound
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TECHNICAL FIELD
The present invention relates to a bicyclic compound having an acetyl-CoA carboxylase (in the present specification, sometimes to be abbreviated as ACC) inhibitory action, which is useful for the prophylaxis or treatment of obesity, diabetes, hypertension, hyperlipidemia, cardiac
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