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Stem Cell Educator Therapy Treat the Viral Inflammation in COVID-19

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This is a prospective, two-arm, partially masked, single center clinical study to assess the safety, feasibility, and efficacy of SCE therapy for the treatment of patients with SARS-CoV-2 infection. Patients will be evaluated by the study principal investigator or co-investigators. Informed consent

Wound Healing After Tooth Extraction in Individuals With Type 1 Diabetes Mellitus

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This prospective, longitudinal, case-control study will include 30 subjects with type 1 diabetes mellitus who require extraction of 1 or more erupted teeth, which will make part of study group (SG). Other 30 healthy subjects, without diabetes mellitus, in need of tooth extraction will make part of

Phenomics in Autoimmune and Inflammatory Diseases

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The family of inflammatory/autoimmune systemic diseases (IAD) represents a large group of human diseases. For most if not all of these IAD, the pathophysiological processes or exact causes remain poorly understood. Progresses in molecular understanding of these IAD have led to realize that these are

Fructose and Glucose and TAS1R2 in Type 1 Diabetes

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INTRODUCTION: Fructose is transported via the portal vein to the liver, where is rapidly taken up by hepatocytes and phosphorylated to fructose-1-phosphate independent of insulin action by the enzyme fructokinase. Thus, under normal conditions, fructose is converted mainly to glucose, glycogen, and

R-FACT Study:Risk Factors for Alloimmunization After Red Blood Cell Transfusions

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Introduction: Individuals exposed to red blood cell (RBC) alloantigens through transfusion, pregnancy, or transplantation may produce antibodies against the alloantigens expressed by RBCs. Although the incidence of these events is debated and ranges between percentages of 1-6% in single transfused

Anti-inflammatory Therapy With Anakinra in Newly Diagnosed Type 1 Diabetes

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Type 1 diabetes mellitus (T1D) is caused by autoimmune and autoinflammatory destruction of the insulin-producing beta cells in the pancreatic islets of Langerhans. Historically, treatment for this condition has consisted of insulin replacement therapy and dietary modification. Recent studies have

Does Warming Mothers During Cesarean Delivery Help Keep Babies Warm When Delivered?

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Maternal hypothermia during Cesarean delivery is predominately caused by a combination of neuraxial anesthesia and exposure of abdominal contents and skin to the low temperatures of the operating room (OR). Since maternal temperature and fetal temperature are intimately related, neonates experience

Autologous Dendritic Cell Therapy for Type 1 Diabetes Suppression: A Safety Study

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In this study, volunteers with established type 1 diabetes that requires insulin replacement who do not exhibit any diabetes-related complications or any other clinical pathology will first undergo complete physical, biochemical and immunological evaluation. Monocyte-derived autologous dendritic

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