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dysarthria/atrophie
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A case of frontotemporal lobar degeneration with progressive dysarthria.
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We investigated the evolution of the neurological and neuropsychological characteristics in a right-handed woman who was 53-years-old at the onset and who showed personality changes and behavioral disorders accompanied by progressive dysarthria. She had hypernasality and a slow rate of speech with
The place of perceptual analysis of dysarthria in the differential diagnosis of corticobasal degeneration and Parkinson's disease.
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OBJECTIVE
To characterize the dysarthria in patients with corticobasal degeneration (CBD) and determine if analysis of speech in isolation helps to distinguish CBD patients from patients with Parkinson's disease (PD).
METHODS
60 subjects were assessed by means of perceptual analysis of speech: 15
Dysarthria and orofacial apraxia in corticobasal degeneration.
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The authors evaluated dysarthria and orofacial apraxia (OFA) in 10 patients with a clinical diagnosis of corticobasal degeneration (CBD). Nine patients were slightly dysarthric according to the French version of the Frenchay Dysarthria Assessment, which evaluates the motricity of the components of
Nasometric Scores in spinal and bulbar muscular atrophy - Effects of palatal lift prosthesis on dysarthria and dysphagia.
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Spinal and bulbar muscular atrophy (SBMA) is a hereditary neuromuscular disease affecting only males characterized by progressive muscular atrophy and weakness in bulbar and limb muscles. The present study aimed to evaluate the features of velopharyngeal dysfunction (VPD) in SBMA subjects by an
Characteristics of the dysarthria of multiple system atrophy.
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OBJECTIVE
To characterize the dysarthria in patients with multiple system atrophy (MSA).
METHODS
Motor speech examinations, consisting of oral motor, oral agility, and perceptual speech analysis, were performed on 46 patients with MSA.
METHODS
University department of neurology referral
Dysarthria enhancement mechanism under external clear speech instruction in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy.
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Clear speech refers to intentionally modifying conversational speech to maximise intelligibility. This study aimed to compare the speech behaviour of patients with progressive supranuclear palsy (PSP), multiple system atrophy (MSA) and Parkinson's disease (PD) under conversational and clear speech
Effects of penicillamine therapy and low-copper diet on dysarthria in Wilson's disease (hepatolenticular degeneration).
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[A study of articulatory dynamics in the dysarthrias. Part I: Cerebellar degeneration (author's transl)].
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Dysarthria and pathological laughter/crying as presenting symptoms of corticobasal-ganglionic degeneration syndrome.
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Primary progressive dysarthria as the initial presentation of corticobasal degeneration: A case report.
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SCA-12: Tremor with cerebellar and cortical atrophy is associated with a CAG repeat expansion.
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OBJECTIVE
To characterize the clinical and neuroradiologic features of a new spinocerebellar ataxia, SCA-12, in the index family.
BACKGROUND
The authors recently linked SCA-12 to a novel CAG repeat expansion on chromosome 5q31-33 that is located within the 5' region of PPP2R2B, a gene encoding a
Spastic paraplegia, optic atrophy, and neuropathy is linked to chromosome 11q13.
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We report an autosomal recessive neurodegenerative disorder in 25 white members from a large inbred Brazilian family, 22 of whom were evaluated clinically. This condition is characterized by (1) subnormal vision secondary to apparently nonprogressive congenital optic atrophy; (2) onset of
[Evaluation of motor speech function in the diagnosis of various forms of dysarthria].
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Perceptual analysis is not sufficient enough to identify specific dysarthria types. In order to improve the discrimination between dysarthria types, we developed a standardized evaluation of different functions controlling speech motor performances. This was applied to 90 patients suffering from
Pseudobulbar dysarthria in the initial stage of motor neuron disease with dementia: a clinicopathological report of two autopsied cases.
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We retrospectively analyzed the clinical features of two cases of neurodegenerative disease, whose initial symptoms were motor speech disorder and dementia, brought to autopsy. We compared the distributions of pathological findings with the clinical features. The main symptom of speech disorder was
Paraneoplastic degeneration of the substantia nigra with dystonia and parkinsonism.
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A 42-year-old woman suffered unexplained weight loss followed by action tremor and difficulty initiating gait. Three months after onset of symptoms, infiltrating ductal carcinoma of the breast, metastatic to liver and lymph nodes, was diagnosed and treated briefly with cyclophosphamide,
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