Daily functional treatment consisted of seven fish oil softgels (1.7g EPA+DHA), two dark chocolate truffles containing plant sterol esters and two green tea sachets.

Control treatment consisted of seven soy bean oil softgels, two regular dark chocolate truffles and two anise tea sachets

Cardiovascular Diseases

Omega 3 fatty acids, plant sterols and polyphenols

Functional treatment

Control treatment

Combined Bioactive Therapy Effects Over Cardiovascular Markers in Statin Treated Patients

Complementary Therapy of Omega 3 Fatty Acids, Plant Sterols and Polyphenols Over Cardiovascular Markers in Statin Treated Patients

Adriana Bertolami

MD. PhD

Instituto Dante Pazzanese de Cardiologia

Obesity

Dyslipidemia

Subjects will be provided with and instructed to consume the equivalent of 20oz. reduced fat milk per day for 3 weeks

Reduced Fat Milk

Subjects will be provided with and instructed to consume 2 cans (24oz) of sugar sweetened soda per day for 3 weeks

Sugar Sweetened Soda

Cholesterol Research Center

Soda and Milk Study

Effects of Replacing Sugar Sweetened Beverages With Milk on Metabolic Factors in Overweight and Obese Adolescents

UCSF Benioff Children's Hospital Oakland

Almond Board of California

This group is receiving omega-3 supplement.

This group is receiving the placebo comparator.

Chagas Cardiomyopathy

The group omega-3 receives 5 capsules / day, each capsule containing 1100mg of lipids, and 600 mg of omega-3, 3g of omega-3 per day (1.8 g EPA and 1.2 g DHA) for a period of 8 weeks.

Omega-3

The group placebo receives 5 capsules / day of corn oil containing 1100mg each, for a period of 8 weeks.

Placebo Comparator

Evandro Chagas Institute of Clinical Research

Effects of Omega-3 Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas Cardiomyopathy

Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas Cardiomyopathy: a Randomized Controlled Clinical Trial

The primary endpoint of this study will be the cytokine profile. IL-1, IL-2, IL-4, IL-6, IL-10, TNF-alpha, IFN-γ, and TGF-β will be measured in the serum of patients using specific sandwich enzyme-linked immunosorbent assays. Capture and detection antibodies will be obtained from eBioscience (San Diego, CA, USA).

Total cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-c) will be measured with enzymatic-colorimetric assays using Siemens reagents on a Siemens Dimension RXL chemistry analyzer (Siemens Healthcare Diagnostics, Tarrytown, NY, USA). Low-density lipoprotein cholesterol (LDL-c) and VLDL-c will be calculated according to the Friedewald equation

The anthropometric assessment will consist of body mass index (BMI), waist circumference, tricipital skinfold thickness, and arm circumference.

dyslipidemias/maïs

Combined Bioactive Therapy Effects Over Cardiovascular Markers in Statin Treated Patients

Soda and Milk Study

Effects of Omega-3 Supplementation on the Cytokine and Lipid Profiles in Patients With Chronic Chagas Cardiomyopathy

Effect of Replacing HFCS With Sucromalt in Subjects With Raised Waist Circumference

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