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5-HT.sub.2C receptor agonists and compositions and methods of use

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Obesity is a life-threatening disorder in which there is an increased risk of morbidity and mortality arising from concomitant diseases such as type II diabetes, hypertension, stroke, cancer, and gallbladder disease. Obesity is now a major healthcare issue in the Western World and increasingly in

5-HT.sub.2C receptor agonists and compositions and methods of use

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Obesity is a life-threatening disorder in which there is an increased risk of morbidity and mortality arising from concomitant diseases such as type II diabetes, hypertension, stroke, cancer, and gallbladder disease. Obesity is now a major healthcare issue in the Western World and increasingly in

5-HT2C receptor agonists and compositions and methods of use

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Obesity is a life-threatening disorder in which there is an increased risk of morbidity and mortality arising from concomitant diseases such as type II diabetes, hypertension, stroke, cancer, and gallbladder disease. Obesity is now a major healthcare issue in the Western World and increasingly in

Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators

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FIELD OF THE INVENTION The present invention relates to acylated spiropiperidine derivatives, their synthesis, and their use as melanocortin receptor (MC-R) ligands useful to modulate bodyweight. More particularly, the compounds of the present invention are ligands of the melanocortin-4 receptor

Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators

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FIELD OF THE INVENTION The present invention relates to acylated spiropiperidine derivatives, their synthesis, and their use as melanocortin receptor (MC-R) ligands useful to modulate bodyweight. More particularly, the compounds of the present invention are ligands of the melanocortin-4 receptor

Method for treating occlusive vascular diseases & wound healing

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FIELD OF THE INVENTION Compositions and methods for treatment of wound healing, occlusive peripheral vascular, carotid and coronary disease are disclosed. The compositions and methods allow treatment of diseases associated with occlusion of coronary vessels, for example, by promoting growth of new
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