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esophageal neoplasms/fièvre
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[Radiotherapy of esophageal cancer using local hyperthermia and metronidazole (polyradiomodification)].
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The results of a dynamic course of radiotherapy alone and in combination with local hyperthermia and metronidazole were studied in 107 patients with esophageal cancer. With relation to the methods applied the patients were divided into 4 groups: the 1st group (40 patients) was given radiotherapy,
Thermometric analysis of intra-cavitary hyperthermia for esophageal cancer.
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Thermometric analysis was carried out in 51 patients with esophageal cancer treated with intra-cavitary hyperthermia combined with radio chemotherapy, to test whether temperature index (T20, T50) and T90) could be used as an indicator for tumour control. Hyperthermia was administered by
Preliminary report on the treatment of esophageal cancer by intraluminal microwave hyperthermia and chemotherapy.
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Thirty-two cases of esophageal cancer were treated with thermochemotherapy from August 1984 to June 1985. A combination of bleomycin (20 mg per session iv) and cisplatin (0.5-0.9 mg/kg per session as low dose and 1.0-2.0 mg/kg per session as high dose), or of bleomycin, cisplatin (high dose), and
Synergistic antiproliferative effect of delta 12-prostaglandin J2 (delta 12-PGJ2) and hyperthermia on human esophageal cancer cell lines.
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delta 12-PGJ2, one of the cyclopentenone prostaglandins and the ultimate metabolite of prostaglandin D2, has been reported to have potent antiproliferative activity on various tumor cells in vitro and in vivo. In this study, the combined effect of delta 12-PGJ2 and hyperthermia on six established
[Experimental studies on combined chemotherapy with hyperthermia and ethanol for advanced esophageal cancer. I. In vitro effects of combined treatments on 3H-TdR uptake of FM3A cells by microculture method].
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The combined effects of hyperthermia, bleomycin and ethanol were investigated using FM3A tumor cells in vitro. Cytotoxicity of the heating was found at temperatures higher than about 41 degrees C, and remarkably increased at 43 degrees C. Cytotoxicity of ethanol was found at concentrations higher
Effectiveness of hyperthermia and radiation treatments for patients with esophageal cancer predicted by the succinate dehydrogenase inhibition test.
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We used in vitro succinate dehydrogenase inhibition test (SDI test) to predict the combined effects of hyperthermia and irradiation on specimens of esophageal cancer obtained at endoscopy. The mean activity of succinate dehydrogenase (SD) after combined treatment of 6 Gy of irradiation and 43.0
Preoperative chemoradiation combined with regional hyperthermia for patients with resectable esophageal cancer.
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OBJECTIVE
To analyse the treatment results of neo-adjuvant chemoradiation combined with regional hyperthermia in patients with resectable esophageal cancer.
METHODS
Between August 2003 and December 2004, 28 patients entered a phase II study combining chemoradiation over a 4.5-week period with five
[Intracavitary microwave hyperthermia combined with external irradiation in the treatment of esophageal cancer].
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A randomized trial of intracavitary microwave hyperthermia combined with external irradiation (R + H) versus radiation (R) alone in the treatment of esophageal cancer was performed from Feb. 1986 to Feb. 1988. In the R group, radiation was given by 8 MV X-ray with 2 Gy/fraction, 5 fractions per week
Early report of correlation between the thermal dosage and the treatment effect of hyperthermia in combination with chemoradiotherapy for esophageal cancer patients.
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OBJECTIVE
It is known to be difficult to determine thermal dosage in clinical tumor treatment. The aim of this study is to examine whether the quantitative heating dose reflects the treatment effect in esophageal cancer.
METHODS
Hyperthermo-chemoradiotherapy was performed on 14 patients with
Prognostic significance of lymphocyte infiltration following preoperative chemoradiotherapy and hyperthermia for esophageal cancer.
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OBJECTIVE
Lymphocyte infiltration (LI) around cancerous lesions is an important immune response. The purpose of this study is to evaluate the prognostic significance of LI after preoperative treatment for esophageal cancer.
METHODS
Preoperative chemoradiotherapy (CR therapy), either bleomycin 30 mg
Hyperthermia induces apoptosis by targeting Survivin in esophageal cancer.
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Hyperthermia is considered the fifth pillar of cancer treatment. It induces cancer cell apoptosis, however, its molecular mechanisms remain unclear. In the present study, the role of Survivin in hyperthermia-induced apoptosis in esophageal cancer was investigated. Different temperatures were used to
Additive effects of cepharanthin in CDDP/hyperthermia combination therapy against transplantable human esophageal cancer in nude mice.
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OBJECTIVE
Additive effects of cepharanthin in CDDP/hyperthermia combination therapy were evaluated.
METHODS
Nude mice bearing a transplantable human esophageal cancer (ES0-2), classified histologically as a moderately differentiated squamous cell carcinoma, were treated with cepharanthin (20 mg/kg
[Experimental studies on combined chemotherapy with hyperthermia and ethanol for advanced esophageal cancer. II. Effects of combined treatments on tumor growth in tumor-bearing mice].
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The combined effects of local hyperthermia, bleomycin and ethanol were investigated using Lewis lung carcinoma (3LL) in female C57BL/6 mice and FM3A tumors in female C3H/He mice. The combined treatments were performed on days 4 and 7 or on days 4, 7 and 10 after tumor implantation. Hyperthermia at
Local hyperthermia for esophageal cancer in a rabbit tumor model: Magnetic stent hyperthermia versus magnetic fluid hyperthermia.
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Magnetic-mediated hyperthermia (MMH) is a promising local thermotherapy approach for cancer treatment. The present study investigated the feasibility and effectiveness of MMH in esophageal cancer using a rabbit tumor model. The therapeutic effect of two hyperthermia approaches, magnetic stent
Magnetic stent hyperthermia for esophageal cancer: an in vitro investigation in the ECA-109 cell line.
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Magnetic stent hyperthermia (MSH) is a novel approach for targeted thermotherapy for esophageal cancer, which is based on the mechanism that inductive heat can be generated by the esophageal stent upon exposure under an alternative magnetic field (AMF). A positive effect of MSH on esophageal cancer
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