Patients assigned to this group will receive IV Remifentanil as an opioid for general anesthesia.

Patients assigned to this group will receive IV Fentanyl as an opioid for general anesthesia.

Breast Disease

Anesthesia

Inflammatory Response

Loading dose: 0.5 mcg/kg Maintenance dose: 1 mcg/kg/minute

Remifentanil

Loading dose: 2 mcg/kg Maintenance dose: 0.4 mcg/kg/30-minutes

Fentanyl

Sanglah General Hospital

Inflammatory Effect Comparison Between Fentanyl and Remifentanil in Mastectomy Under General Anesthesia

Christopher Ryalino

Principal Investigator

Udayana University

This is a single-blind, randomized control trial. It provides a controlled treatment of general anesthesia with an opioid regimen between remifentanil and fentanyl.

The opioid selection disguised to the patient. Eligible subjects will be randomized so that each research subject has the same opportunity to be included in both groups.

This arm will receive -in addition to standard therapy for sepsis and septic shock-Neostigmine methylsulfate ampoule diluted in normal saline, and administered as continuous infusion for five days. The rate of infusion is 0.2 mg/hr.

This arm will receive the standard therapy for sepsis and septic shock only and followed for five days.

Sepsis, Septic Shock

Neostigmine continuous infusion plus standard therapy for sepsis and septic shock.

Neostigmine

Standard therapy for sepsis and septic shock

Standard therapy

Tanta University Hospital

Adjuvant Use of Neostigmine in Sepsis and Septic Shock.

Safety and Efficacy of Neostigmine Infusion as Adjuvant Therapy in Sepsis and Septic Shock

Increase in SOFA score is associated with worse outcome.

Mona Mohammed El-Tamalawy

Assistant lecturer

Mansoura University

Systemic Inflammatory Response Syndrome

Tungs' Taichung MetroHarbour Hospital

Serum Level of Lipopolysaccharide-binding Protein (LBP) and Atherosclerosis in Hemodialysis Patients

Association of Lipopolysaccharide-binding Protein (LBP) and Atherosclerotic Vascular Disease in Taiwanese Hemodialysis Patients

Incident atherosclerotic vascular events in HD patients

The association of LBP with all-cause mortality

TNF-alpha, Interleukin-10(IL-10), Interleukin-6 (IL-6) and soluble (sCD14) are measured using an enzyme-linked immunosorbent assay (ELISA) annually

Tungs’ Taichung Metroharbour Hospital

Rosacea patients who were between the ages of 18-70, having no systemic illness and who were not smoking.
Obtaining a blood sample; TOC, TAC, OSI, PON-1, ARES, MPO, TNF-α, IL-1β, MMP-1 and MMP-9 levels in venous blood were measured Reflectance confocal microscopy; 1mm2-sized 10 images were taken from right cheek and forehead; the number of demodex, follicle, the number of mite per follicle, the number of infested follicle and the number of mite per infested follicle were calculated with RCM. And photoaging severity were also assessed by using RCM. Sebum rate at forehead and right cheek were evaluated with sebumeter. Dermoscopic photoaging scale were assessed by using video dermoscopy.

Healthy volunteers who were compatible in terms of age, sex and skin phenotype, having no systemic illness and who were not smoking.
Obtaining a blood sample; TOC, TAC, OSI, PON-1, ARES, MPO, TNF-α, IL-1β, MMP-1 and MMP-9 levels in venous blood were measured Reflectance confocal microscopy; 1mm2-sized 10 images were taken from right cheek and forehead; the number of demodex, follicle, the number of mite per follicle, the number of infested follicle and the number of mite per infested follicle were calculated with RCM. And photoaging severity were also assessed by using RCM. Sebum rate at forehead and right cheek were evaluated with sebumeter. Dermoscopic photoaging scale were assessed by using video dermoscopy.

Rosacea

Total oxidant capacity (TOC), total antioxidant capacity (TAC), oxidative stress index (OSI), paraoxonase-1 (PON-1), aryl esterase (ARES), myeloperoxidase (MPO), tumor necrosis factor-alpha (TNF-α), interleukin-1beta (IL-1β), matrix metalloproteinase-1 (MMP-1) and matrix metalloproteinase-9 (MMP-9) levels in venous blood were measured.

Obtaining a blood sample

1mm2-sized 10 images were taken from right cheek and forehead; the number of demodex, follicle, the number of mite per follicle, the number of infested follicle and the number of mite per infested follicle were calculated with RCM. And photoaging severity were also assessed by using RCM.

Reflectance confocal microscopy

Sebum rate at forehead and right cheek were evaluated with sebumeter

Sebumeter

Dermoscopic photoaging scale were assessed by using video dermoscopy.

esterase/nécrose

Inflammatory Effect Comparison Between Fentanyl and Remifentanil in Mastectomy Under General Anesthesia

Adjuvant Use of Neostigmine in Sepsis and Septic Shock.

Serum Level of Lipopolysaccharide-binding Protein (LBP) and Atherosclerosis in Hemodialysis Patients

Demodex Density, Immune Response and Oxidative Stress in Rosacea Patients

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