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fungemia/créatinine
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Measurement of serum D-arabinitol/creatinine ratios for initial diagnosis and for predicting outcome in an unselected, population-based sample of patients with Candida fungemia.
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D-Arabinitol (DA) is a useful diagnostic marker for candidiasis in patients with neutropenia and other high-risk groups, but its use in unselected patients with a broad range of underlying diseases and conditions has not been studied. We used an automated enzymatic fluorometric assay to measure
[Study of prognostic factors and estimation of prognosis in patients with fungemia].
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BACKGROUND
The estimation of prognosis is necessary in the treatment of fungemia because of its high mortality rate. We studied prognostic factors and estimated prognosis by scoring clinical and laboratory findings in 41 patients with fungemia treated at Tenri Hospital between 1976 and
Candida glabrata Fungemia. Clinical features of 139 patients.
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Candida species are now the fourth leading cause of nosocomial bloodstream infection in hospitalized patients, and non-Candida albicans species now surpass Candida albicans. The clinical features of the most common non-Candida albicans species, Candida (Torulopsis) glabrata, have not been well
Long-term survival following bacteremia or fungemia.
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OBJECTIVE
To delineate long-term survival after an episode of bacteremia or fungemia and risk factors for mortality.
METHODS
Cohort study.
METHODS
A 900-bed university hospital in Israel.
METHODS
Study group comprising 1991 patients 18 years of age or older in whom bacteremia or fungemia were
[Saccharomyces cerevisiae fungemia in an elderly patient following probiotic treatment].
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Saccharomyces cerevisiae, known as baker's yeast, is also used as a probiotic agent to treat gastroenteritis by modulating the endogenous flora and immune system. However, since there have been increasing reports of fungemia due to S.cerevisiae and its subspecies S.boulardii, it is recommended that
Candida fungemia in neonates treated with fluconazole: report of forty cases, including eight with meningitis.
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OBJECTIVE
To assess efficacy and safety of fluconazole in neonates with Candida fungemia.
METHODS
Multicenter prospective protocol of all fungemias appearing between January 1, 1993, and December 31, 1997, in four major university hospitals.
RESULTS
Forty neonates, 28 of them with very low birth
Neonatal fungemia and amphotericin B.
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Disseminated candidemia is a common nosocomial infection in the neonatal intensive care unit, though only a few studies have reported the outcome of amphotericin B therapy in neonatal candidiasis. Our treatment regimen consisted of an initial daily amphotericin B dose of 0.5 mg/kg. (For infants
Prediction of mortality in patients with bacteremia: the importance of pre-existing renal insufficiency.
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Pre-existing renal insufficiency serves as a common risk factor in the development of acute renal failure. Acute renal failure is a common finding in patients with bacteremia and is associated with poor prognosis. A total of 2722 consecutive patients 18 years old or older, fulfilling strike criteria
Hypercalcemia associated with infection by Cryptococcus neoformans and Coccidioides immitis.
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BACKGROUND
Of the 13 reported cases of hypercalcemia associated with fungal infection, 1 was caused by Cryptococcus neoformans and probably mediated by increased levels of 1,25-dihydroxyvitamin D [1,25(OH)2D]. Eight others were associated with Coccidioides immitis, of which only 2 had measured
Candidate prognostic indicators in cats with histoplasmosis treated with antifungal therapy.
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Objectives The aim of this study was to retrospectively identify candidate prognostic indicators in cats with histoplasmosis treated with antifungal therapy. Methods Medical records of cats diagnosed with histoplasmosis were reviewed. Candidate prognostic indicators were assessed for an association
Enantioselective measurement of the Candida metabolite D-arabinitol in human serum using multi-dimensional gas chromatography and a new chiral phase.
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A multi-dimensional gas chromatographic method was developed to measure the Candida metabolite D-arabinitol enantioselectively in human serum. The heptafluorobutyrate derivatives of D-arabinitol, L-arabinitol and ribitol (internal standard) were separated from other serum constituents with a 60 m X
Renal tolerance with the use of intralipid-amphotericin B in low-birth-weight neonates.
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Amphotericin B is still the first-line therapy for neonatal fungal infections. With several comparative trials of intralipid-based amphotericin B (IL-AmB) demonstrating its clinical effectiveness and reduced renal toxicity in adults, we examined the renal tolerance and infection outcome in
Safety, tolerance, and pharmacokinetics of amphotericin B lipid complex in children with hepatosplenic candidiasis.
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The safety, tolerance, and pharmacokinetics of amphotericin B lipid complex (ABLC) were studied in a cohort of pediatric cancer patients. Six children with hepatosplenic candidiasis (HSC) received 2.5 mg of ABLC/kg of body weight/day for 6 weeks for a total dosage of 105 mg/kg. Mean serum creatinine
Serious renal impairment is associated with long-term parenteral nutrition.
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Thirty-three current long-term total parenteral nutrition (TPN) patients (13 men, 20 women) aged 21 to 79 years were prospectively studied to evaluate their change in glomerular filtration rate since beginning TPN. Creatinine clearance (CrCl) from the subject's initial home TPN clinic visit and at
An evaluation of serodiagnostic tests in patients with candidemia: beta-glucan, mannan, candida antigen by Cand-Tec and D-arabinitol.
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The serodiagnostic tests, beta-glucan, mannan, candida antigen by Cand-Tec, and D-arabinitol were evaluated in 10 patients with candidemia, 14 patients with suspected fungemia, and 10 healthy persons. By blood culture or lysis centrifugation, C. albicans was isolated from 5 patients, C. parapsilosis
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