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gamma glutamyl transferase/céphalée
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Nilotinib in locally advanced pigmented villonodular synovitis: a multicentre, open-label, single-arm, phase 2 trial.
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BACKGROUND
Pigmented villonodular synovitis (alternatively known as diffuse-type giant cell tumour) is a rare, locally aggressive tumour driven by a specific translocation resulting in the overexpression of colony-stimulating factor 1 (CSF1). CSF1 receptor (CSF1R) inhibitors (ie, tyrosine kinase
Enfuvirtide: a fusion inhibitor for the treatment of HIV infection.
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BACKGROUND
Drug resistance continues to be a major challenge in the treatment of HIV-1 infection. Virtually all currently available antiretroviral medications inhibit the viral reverse transcriptase or protease. Enfuvirtide is the first fusion inhibitor approved by the US Food and Drug
Ursodeoxycholic acid modulates cyclosporin A oral absorption in liver transplant recipients.
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The aim was to study the ursodeoxycholic acid (UDC) effect on the cyclosporin A (CsA) pharmacokinetics after oral administration of the microemulsion formulation Neoral (CsA-ME) in liver transplant recipients, and test the potential protective effect of this bile acid on liver and renal
The tolerability and safety profile of eslicarbazepine acetate in neurological disorders.
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Occupational infection in an offal porter: a case of Q fever.
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This case report describes the job activities of an offal porter who developed Q fever while processing livers from sheep. The diagnosis was confirmed by an increase in specific serial antibody titre. The main clinical features were anorexia, nausea, headache, pyrexia and elevated gamma-glutamyl
Comparative toxicity and safety profile of fenofibrate and other fibric acid derivatives.
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It is estimated that there are approximately six million patient-years of clinical experience with fenofibrate among physicians outside of the United States. A review of the European literature and unpublished studies supplied by the manufacturer (Laboratoires Fournier, Dijon, France) has been
Epidemiological and clinical characteristics of COVID-19 patients in Hengyang, Hunan Province, China
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Background: In December 2019, an ongoing outbreak of coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China. The characteristics of COVID-19 patients treated in local hospitals in Wuhan are not fully representative of
Silymarin: a review of its clinical properties in the management of hepatic disorders.
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The mechanisms of action of silymarin involve different biochemical events, such as the stimulation of the synthetic rate of ribosomal RNA (rRNA) species through stimulation of polymerase I and rRNA transcription, protecting the cell membrane from radical-induced damage and blockage of the uptake of
Genotypes of Epstein-Barr virus (EBV1/EBV2) in individuals with infectious mononucleosis in the metropolitan area of Belém, Brazil, between 2005 and 2016
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Two types of Epstein Barr virus (EBV1/EBV2) have been shown to infect humans. Although their genomes are similar, the regions containing the EBNA genes differ. This study aimed to characterize the EBV genotypes of infectious mononucleosis (IM) cases in the metropolitan region of Belém, Brazil, from
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