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.DELTA.9 Tetrahydrocannabinol (.DELTA.9 THC) solution metered dose inhaler
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DESCRIPTION
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention is generally related to the therapeutic use of .DELTA..sup.9 Tetrahydrocannabinol (.DELTA..sup.9 THC). In particular, the invention provides a metered dose inhaler (MDI) for the aerosol administration of .DELTA..sup.9
.DELTA.9 tetrahydrocannabinol (.DELTA.9 THC) solution metered dose inhalers and methods of use
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention is generally related to the therapeutic use of .DELTA..sup.9 Tetrahydrocannabinol (.DELTA..sup.9 THC). In particular, the invention provides a metered dose inhaler (MDI) for the aerosol administration of .DELTA..sup.9 THC to
ABHD6 and dual ABHD6/MGL inhibitors and their uses
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BACKGROUND
Cannabinoid receptors, CB1 and CB2, are part of the endocannabinoid system (ECS), which consists of cannabinoid receptors, endogenous endocannabinoids anandamide (AEA) and 2-arachindonoylglycerol (2-AG) and the hydrolytic enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol
Benzimidazolone derivatives as CB2 receptor ligands
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone derivatives. These compounds have selective cannabinoid(CB)2 receptor binding activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the
Sulfonyl benzimidazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to sulfonyl benzimidazole derivatives. These compounds have selective cannabinoid (CB)2 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
Sulfonamide derivatives as D3-receptor ligands
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FIELD OF THE INVENTION
The present invention relates to new D.sub.3 dopamine receptor subtype selective ligands of formula (I) and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof which are useful in the therapy and/or prevention of
Derivatives of amide analogs of certain methano bridged quinolizines
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This invention relates to novel amide derivatives of certain 2,6-methano-2H-quinolizines-type compounds, to the intermediates and processes for their preparation, to their ability to antagonize the effects of serotonin at the 5HT.sub.3 receptors, and to their end-use application in the treatment of
Process for the preparation of 1,5--carboxylic acid derivatives
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FIELD OF THE INVENTION
The present invention relates generally to processes for the preparation of pharmaceutical compounds and compositions useful in the treatment of disorders and diseases of the central nervous system (CNS). More specifically, the present invention relates to the preparation of
Urea compounds and their use as enzyme inhibitors
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FIELD OF THE INVENTION
The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty
Urea compounds and their use as enzyme inhibitors
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FIELD OF THE INVENTION
The present invention relates to compounds and their uses, and in particular to compounds and their therapeutic use in the treatment or prevention of conditions having an association with substrates, such as the neurotransmitter anandamide, which are broken down by the fatty
Cannabinoid receptor agonists
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BACKGROUND OF THE INVENTION
This invention relates to certain novel octahydro-3-alkoxy-9-alkyl-phenanthridines and derivatives thereof and pharmaceutically acceptable acid addition salts thereof useful as antiinflammatory, analgesics, immunosuppressive, antiemetic and intraocular pressure reducing
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