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guanosine/inflammation

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Isoform specific inhibition for treatment of pain and reduction of anesthetic threshold

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TECHNICAL FIELD OF THE INVENTION BACKGROUND OF THE INVENTION Nitric oxide (NO), which serves as an intracellular messenger, is implicated in a number of processes in the central nervous system. In the spinal cord, considerable evidence has demonstrated that NO contributes to the development of

Isoform specific inhibition for treatment of pain and reduction of anesthetic threshold

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TECHNICAL FIELD OF THE FIELD INVENTION BACKGROUND OF THE INVENTION Nitric oxide (NO), which serves as an intracellular messenger, is implicated in a number of processes in the central nervous system. In the spinal cord, considerable evidence has demonstrated that NO contributes to the development of

Isoform specific inhibition for treatment of pain and reduction of anesthetic threshold

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BACKGROUND OF THE INVENTION Nitric oxide (NO), which serves as an intracellular messenger, is implicated in a number of processes in the central nervous system. In the spinal cord, considerable evidence has demonstrated that NO contributes to the development of hyperalgesia in models of acute and

Blocking induction of tetrahydrobioterin to block induction of nitric oxide synthesis

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TECHNICAL FIELD This invention is directed to a novel method of inhibiting the induction of nitric oxide formation in biological systems by bacterial endotoxins and cytokines. BACKGROUND OF THE INVENTION For several decades nitroglycerin has been administered to humans as a vasodilating agent in the

Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis

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This invention was made at least in part with Government support under Grants HL46403 from the National Institutes of Health. TECHNICAL FIELD This invention is directed to a novel method of inhibiting the induction of nitric oxide formation in biological systems by bacterial endotoxins and

Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis

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TECHNICAL FIELD This invention is directed to a novel method of inhibiting the induction of nitric oxide formation in biological systems by bacterial endotoxins and cytokines. BACKGROUND OF THE INVENTION For several decades nitroglycerin has been administered to humans as a vasodilating agent in the
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