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The nicotine dependence concept is well founded and it is clear that it is necessary to assess this before treatment starts. Behavioural dependence, although difficult to disentangle from the pharmacological dependence, is also important. With the development of tools for assessing behavioural
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To further evaluate whether transsynaptic mechanisms account for stress-induced changes in adrenomedullary preproenkephalin mRNA (ppEnk mRNA), neonatal rats were made hypoglycemic at a time when synapses are non-functional (less than 10 days postnatal age). While ppEnk mRNA in medullae from adult
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The present article is focused on tobacco smoking, alcohol consumption, and necessary physical activity, and how they contribute to everyday life of diabetic patients. The article is based on a study comprising 106 such patients, treated in two leading centres of diabetological care in the City of
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BACKGROUND
* Only one other study (Becker et al.) has reported on the influence of smoking cessation and smoking resumption on inhaled insulin pharmacokinetics and glucodynamics, concluding that the rapid changes associated with smoking resumption carry the risk for hypoglycaemia and thus should not
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A 2-year study with six soils and four levels of Meloidogyne incognita in microplots was designed to determine the effects of these parameters on nematode activity and tobacco yield and quality. Key components under study were affected by soil, nematode level, and season (year-cultivar). In 1980,
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Exposure to tobacco smoke is related to changes in energy balance regulation and several endocrine dysfunctions. Previously, we showed that maternal nicotine (the main addictive compound of tobacco) exposure exclusively during lactation affects biochemical profiles in mothers, milk, and pups. As the
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The availability of energy appears to exert important regulatory functions in pituitary-adrenal stress responses. In two studies, the effects of short-term fasting and subsequent glucose administration on the free cortisol response to psychological stress and nicotine consumption were investigated.
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Recurrent exposure to hypoglycemia can impair the normal counterregulatory hormonal responses that guard against hypoglycemia, leading to hypoglycemia unawareness. This pathological condition known as hypoglycemia-associated autonomic failure (HAAF) is the main adverse consequence that prevents
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We have previously reported an impaired arginine vasopressin (AVP) response to insulin-induced hypoglycemia in obese men, suggesting a hypothalamic-posterior pituitary disorder in obesity. In the present study, we examined the AVP response to other releasing stimuli with a central site of action.
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BACKGROUND
We hypothesize that depression in type 2 diabetes might be associated with poor glycemic control, in part due to suboptimal self-care. We tested this hypothesis by examining the associations of depression with clinical and laboratory findings in a multicenter survey of Chinese type 2
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The effects of a full preparation (FP) and a modified preparation (MP) of cows' urine concoction (CUC) on the level of plasma glucose in fasted male Wistar rats were investigated. The results showed that FP caused significant hyperglycaemia; while the MP and a control injection using 0.9% saline had
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TIA is a serious condition and a medical emergency requiring immediate evaluation and treatment to prevent a stroke. Confirmation of diagnosis is vital. Medical conditions like hypoglycaemia, migraine etc which mimic TIA should be identified. TIA syndrome in carotid territory needs special
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