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6 résultats
Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease
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TECHNICAL FIELD OF THE INVENTION
The present invention is related to a multi-dose topical ophthalmic composition containing a 1H-indole-1-carboxamide and use thereof for treatment of ophthalmic condition or disease. More specifically the present invention relates to a to multi-dose aqueous
Substituted indoles and their use as integrin antagonists
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to novel substituted indole compounds that are antagonists of alpha V (.alpha.v) integrins, for example .alpha..sub.v.beta..sub.3 and .alpha..sub.v.beta..sub.5 integrins, their pharmaceutically acceptable salts, and
Substituted indoles and their use as integrin antagonists
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to novel substituted indole compounds that are antagonists of alpha V (.alpha.v) integrins, for example .alpha..sub.v.beta..sub.3 and .alpha..sub.v.beta..sub.5 integrins, their pharmaceutically acceptable salts, and
Indole derivatives and drugs containing the same
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TECHNICAL FIELD
This invention relates to an indole derivative which has excellent action of inducing neuron differentiation, and which is useful as a prophylactic or therapeutic drug for brain dysfunction, neuropathy, or the like caused by loss or injury of whole neuron including the brain cell.
2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents
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BACKGROUND OF THE INVENTION
The use of hormone replacement therapy for bone loss prevention in post-menopausal women is well precedented. The normal protocol calls for estrogen supplementation using such formulations containing estrone, estriol, ethynyl estradiol or conjugated estrogens isolated
Substituted thiazolidinedione indazoles, indoles and benzotriazoles as estrogen-related receptor-.alpha. modulators
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FIELD OF THE INVENTION
The present invention relates to certain novel compounds, methods for preparing compounds, compositions, intermediates and derivatives thereof and for treating conditions such as cancer, arthritis, inflammatory airway disease, and metabolic disorders. More particularly, the
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