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6 résultats
Indole derivatives with affinity for the cannabinoid receptor
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BACKGROUND OF THE INVENTION
The terms cannabinoid or cannabimimetic compound apply to compounds which produce a physiological effect similar to that of the plant Cannabis Sativa, or a compound that has affinity for the cannabinoid receptors CB.sub.1 or CB.sub.2. See Matsuda, L.; Lolait, S. J.;
Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family
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CROSS REFERENCE TO RELATED APPLICATIONS
This application claims the priority benefit of the earlier filing date of Great Britain Application No. 1409464.3, filed on 28 May 2014 and Great Britain Application No. 1409514.5, filed on 29 May 2014, both of which are specifically incorporated herein by
Indoles are cannabinoid receptor ligands
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TECHNICAL FIELD
The present invention relates to indole derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
BACKGROUND OF THE INVENTION
(-)-.DELTA..sup.9-Tetrahydrocannabinol (.DELTA..sup.9-THC), the major
Indoles are cannabinoid receptor ligands
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TECHNICAL FIELD
The present invention relates to indole derivatives, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
BACKGROUND OF THE INVENTION
(-)-.DELTA..sup.9-Tetrahydrocannabinol (.DELTA..sup.9-THC), the major
(Indol-3-yl) heterocycle derivatives as agonists of the cannabinoid CB1 receptor
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The present invention relates to (indol-3-yl)-heterocycle derivatives, to pharmaceutical compositions comprising the same and to the use of these (indol-3-yl)-heterocycle derivatives in therapy, especially in the treatment of pain.
Pain treatment is often limited by the side effects of currently
Cannabinoid type 1 receptor modulators
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FIELD
The present disclosure relates to compounds of the Formula (I) which are cannabinoid type 1 receptor modulators, and their use in the treatment of diseases in which modulation of the receptor is beneficial.
INTRODUCTION
The endocannabinoid system encompasses a family of endogenous eicosanoid
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