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67Ga and 59Fe uptake by tumor cells treated with hyperthermia or hyperthermia plus lanthanum.
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The uptake of 67Ga-citrate and 59Fe-citrate by tumor cells treated with hyperthermia or with hyperthermia plus lanthanum has been studied. The comparison of these results with ion flux determinations (42K) appears to indicate that hyperthermia alone or combined with lanthanum modifies the ionic
Enhancement of hyperthermia lethality by Lanthanum.
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The authors have studied the effects of La3+ during hyperthermia on tumor cells, Trypan blue exclusion and 86Rb release from previously labeled Ehrlich and DS carcinosarcoma ascites cells, indicate an increase of plasma membrane permeability by La3+ as a function of the hyperthermic level. The
Comparative enhancement of hyperthermia lethality on tumor cells by procaine and lanthanum.
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The effects of procaine and lanthanum during hyperthermia of tumor cells were studied by trypan-blue exclusion and by 86Rb release from previously labeled Ehrlich ascites cells. The results indicate that while procaine shows no changes of cell viability and 86Rb outflux, lanthanum alters both
Hyperthermia and cytotoxic drugs. Possible use of lanthanum as a potentiator of hyperthermia.
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Recent studies indicate that differences in membrane fluidity may account for differences of thermal sensitivity. This possibility was studied by using lanthanum, a trivalent cation which is known to displace calcium in a number of biological systems, to modify the structural framework of cell
Effects of hyperthermia and lanthanum on tumor cell leakage.
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The effects of hyperthermia temperature and the presence of lanthanum on the release of Ehrlich's ascites cell molecules labelled with radiophosphorus have been studied. The leakage of intracellular molecules is in relationship with the temperature and the time of incubation. The phenomenon presents
Nanohyperthermia of malignant tumors. I. Lanthanum-strontium manganite magnetic fluid as potential inducer of tumor hyperthermia.
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OBJECTIVE
To synthesize magnetic particles of lanthanum-strontium manganite, prepare the magnetic fluid (MF), evaluate the generation of heat by particles and determine their common toxiсity.
METHODS
Nanoparticles based on the solid solutions of lanthanum-strontium manganite (La(1-x)Sr(x)MnO(3))
Intracellular ionic changes during hyperthermia of tumor cells in the presence of lanthanum.
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The experimental data suggest that permeability changes at the plasma membrane level are the most likely cause of the enhancement of tumor cell killing by hyperthermia in the presence of 1 mM La3+. The interaction of La3+ with the Na+, K+ ATPase and Ca2+-pump ATPase may be the probable cause of
Potentiation of hyperthermia by lanthanum.
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Ag-doped manganite nanoparticles: new materials for temperature-controlled medical hyperthermia.
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The purpose of this study was to introduce newly synthesized nanomaterials as an alternative to superparamagnetic ironoxide based particles (SPIO) and thus to launch a new platform for highly controllable hyperthermia cancer therapy and imaging. The new material that forms the basis for this article
In vivo changes of ionic composition of tumors treated by hyperthermia.
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Experimental tumors submitted in vivo to hyperthermia, in the presence, or not, of lanthanum (La3+), have shown modifications in the concentration of extra- and intracellular cations. Sacrificed immediately after hyperthermia, only the group treated with La3+ presented ionic changes (lower magnesium
Interplay between superparamagnetic and blocked behavior in an ensemble of lanthanum-strontium manganite nanoparticles.
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Magnetic nanoparticles constitute promising tools for addressing medical and health-related issues based on the possibility to obtain various kinds of responses triggered by safe remote stimuli. However, such richness can be detrimental if different performances are not adequately differentiated and
LSMO Nanoparticles Coated by Hyaluronic Acid for Magnetic Hyperthermia.
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Magnetic hyperthermia with the treating temperature range of 41-46 °C is an alternative therapy for cancer treatment. In this article, lanthanum strontium manganates (La1-x Sr x MnO3, 0.25 ≤ × ≤ 0.35) magnetic nanoparticles coated by hyaluronic acid (HA) which possesses the ability of targeting
Lanthanum-Induced Gastrointestinal Histiocytosis.
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A patient with end-stage renal disease (ESRD) on hemodialysis presented with fever, anorexia, and nausea shortly after starting oral lanthanum carbonate for phosphate control. Gastric and duodenal biopsies demonstrated diffuse histiocytosis with intracellular aggregates of basophilic foreign
Hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3 nanoparticles: in vivo studies.
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OBJECTIVE
The aim of this study was to evaluate radiofrequency-induced dextran-coated lanthanum strontium manganese oxide nanoparticles-mediated hyperthermia to be used for tumor regression in mice.
METHODS
Nanoparticles were injected intra-tumorally in melanoma-bearing C57BL/6J mice and were
Role of serotonin in heat adaptation: an experimental study in the conscious young rat.
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The possibility that serotonin may play a role in heat adaptation was examined in a rat model of heat stress (HS). Subjection of animals to acute 4 h HS (but not to 1 h and 2 h duration) in a biological oxygen demand (BOD) incubator (relative humidity 50-55%, wind velocity 20-25 cm/s) resulted in
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