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Duodenal contents reflux-induced laryngitis in rats: possible mechanism of enhancement of the causative factors in laryngeal carcinogenesis.

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OBJECTIVE The main factors considered responsible for the onset of laryngeal cancer are tobacco smoking and alcohol abuse. Recently, gastroesophageal reflux has also been implicated as a causative factor in several laryngeal disorders, including laryngeal cancer. However, the significance of

[Chronic laryngitis--associated factors and voice assessment].

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BACKGROUND Chronic laryngitis may be a predisposing factor for laryngeal carcinoma. METHODS 100 consecutive chronic laryngitis patients were assessed for associated factors for this disease. Voice assessment was undertaken, including objective measurement, subjective assessment of sound and a

Occupational laryngitis caused by formaldehyde: a case report.

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Formaldehyde is commonly accepted to be an allergen and irritant. However, specifically diagnosed occupational respiratory diseases caused by formaldehyde are relatively rare. Occupational laryngitis was diagnosed in a 47-year-old dairy foreman. He had been exposed for 9 years to formaldehyde

[Chronic laryngitis in adults].

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BACKGROUND Chronic laryngitis is a lingering inflammation of the laryngeal mucosa, caused by specific aetiology and often irritative factors. OBJECTIVE To discuss clinic and therapeutic aspects of the pathology. METHODS We report a retrospective stuy about 25 patients treated and followed for non

[Clinical pathology of chronic hyperplastic laryngitis. 2. Clinical, morphological and statistical studies with special reference to precancerous changes].

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Data on 13 different clinical, histological and environmental factors were obtained from 54 patients with hyperplastic laryngitis (HL). They were evaluated by multiple linear factor analysis. HL can be considered to be a complex clinico-morphological entity. Precancerous changes in the larynx were

The effects of allergens and tobacco smoke on the laryngeal mucosa of guinea pigs.

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OBJECTIVE The purpose of this study was to investigate the effects of environmental tobacco smoke (ETS) and house dust mite allergen (HDMA) on the laryngeal mucosa of guinea pigs. METHODS Prospective, controlled animal study. METHODS Sixteen juvenile guinea pigs were randomly assigned to one of four

[Correlation between chronic hyperplastic laryngitis and infection with human papillomaviruses].

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Cancer of the larynx is one of the most prevalent tumors of the head and neck, with its prognosis dependent on early diagnosis. A number of authors have now reported a connection between head and neck cancers and infection with human papilloma virus (HPV). A large number of these tumors has been

Clinical practice guideline: hoarseness (dysphonia).

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OBJECTIVE This guideline provides evidence-based recommendations on managing hoarseness (dysphonia), defined as a disorder characterized by altered vocal quality, pitch, loudness, or vocal effort that impairs communication or reduces voice-related quality of life (QOL). Hoarseness affects nearly

[Laryngeal Tuberculosis Diagnosed in a Pathological Laboratory in Senegal (2011-2015)].

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Laryngeal tuberculosis (LT) is a rare disease. The therapy for LT is easy but the diagnosis remains a challenge for the pathologist and the laryngologist because of the absence of specific signs. The objective was to analyze the epidemiological and pathological profiles of LT cases in Dakar

[Findings in a high-risk group following asbestos exposure. Benefit of ENT examinations in patients with long-term exposure to asbestos].

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OBJECTIVE Laryngeal diseases caused by exposure to asbestos are listed in the current German list of occupational diseases under number 4104. Parallel to a multicenter study to evaluate whether a CT scan should be included in the examinations for occupational diseases according to the German

Laryngeal T regulatory cells in the setting of smoking and reflux.

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The larynx is a mucosal organ rich in lymphatic tissue that is regularly exposed to a multitude of inhaled, ingested, and refluxed microorganisms and irritants. The first line of mucosal immune defense is the barrier, including resident immune cells. T regulatory (Treg) cells are a specialized

[Management of laryngeal cancers].

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With 5,000 cases yearly, laryngeal carcinomas account in France for the third of squamous cell cancers of the upper digestive and respiratory tract. The crude survival rate is 50% at 5 years. Carcinomas of vocal cords are often diagnosed as early stages if dysphonia leads the patients to the ENT

Laryngeal tuberculosis.

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Laryngeal tuberculosis is the most frequent granulomatous disease of the larynx. The disease has changed its behaviour with regard to average age of onset site and type of lesion. Laryngeal tuberculosis is usually secondary to, or at least contemporary with, pulmonary tuberculosis. Other recents

[Therapy and prognosis in 360 laryngeal and hypopharyngeal cancers at the Erfurt ENT clinic 1978-1987].

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We report 316 patients with carcinoma of the larynx and 44 patients with carcinoma of the hypopharynx. The 5-year survival rate for supraglottic carcinoma was 53%, for glottic carcinoma 74%, and for hypopharyngeal carcinoma 18%. The ratio of men to women was 17:1. The risk factors of chronic

[Gastro-esophageal reflux and laryngeal phlogistic disorders: clinical evaluation and multi-electrode pH monitoring].

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Gastro-esophageal reflux (GER) is a complex pathology characterized by many clinical symptoms: gastroenterological (typical symptoms) and odontostomatological, pneumological and, more frequently, otorhinolaryngological (atypical symptoms). For this last manifestations no cause-effect relationship

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