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leukocytosis/potassium
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Pneumatic transport is critical for leukaemic patients with major leukocytosis: what precautions to measure lactate dehydrogenase, potassium and aspartate aminotransferase?
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False elevations of plasma lactate dehydrogenase (LDH), potassium and aspartate aminotransferase (AST) have been described, in relation to haemolysis, occurring most often by mechanical release during phlebotomy or specimen processing. We present the cases of two leukaemic patients with severe
Variable Potassium Concentrations: Which Is Right and Which Is Wrong?
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Reverse pseudohyperkalemia is a term used to describe in vitro, falsely elevated potassium concentrations in plasma specimens that occur in association with extreme leukocytosis and are commonly associated with hematologic malignant neoplasms. Tumor lysis syndrome is an in vivo lysis of tumor cells
Morvan's syndrome associated with antibodies to multiple components of the voltage-gated potassium channel complex.
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We describe a patient presenting with a combination of muscle fasciculations, paresthesias, hyperhidrosis, as well as insomnia, agitation and confusion. He went on to develop psychosis and respiratory failure requiring intensive care. Electromyography confirmed the presence of neuromyotonia and CSF
Multicentric Castleman's disease with voltage-gated potassium channel antibody-positive limbic encephalitis: a case report.
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BACKGROUND
Castleman's disease is a rare lymphoproliferative disorder which occurs in localized and multicentric forms and can mimic lymphoma. Despite its well-known association with certain autoimmune diseases, including paraneoplastic pemphigus and myasthenia gravis, Castleman's disease has not
Pneumatic tube system transport and false hyperkalemia related to leukocytosis: a retrospective analysis.
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[Patient with limbic encephalitis associated with anti-voltage-gated potassium channel antibodies who presented with insomnia and hand tremor].
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A 65-year-old man presented with bilateral postural hand tremor (3 Hz) followed by memory impairment, which improved spontaneously after admission to our hospital. Two weeks after admission, he had another bout of memory impairment and complained of insomnia. Brain magnetic resonance imaging (MRI)
Estimation of granulocyte and lymphocyte potassium in normal subjects and in patients treated with diuretics because of cardiovascular disease: a methodological study.
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A method is described for measuring the potassium content in leukocytes using Percoll (R) density gradient centrifugation. Ninety subjects between 21 and 92 years formed the reference population. The magnesium content in leukocytes could not be estimated because of interaction between the ion and
Pseudohyperkalemia - Potassium released from cells due to clotting and centrifugation - a case report.
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Hyperkalemia is a potentially lethal condition. Pseudohyperkalemia should be always excluded before implementing treatment to prevent inappropriate cause of hypokalemia - equally a potentially lethal condition. Here we present a case report of a 62 year female with chronic myeloproliferative
[Potassium permanganate poisoning in infancy].
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Potassium permanganate intoxication in 3 infant girls (2.5, 2.5 and 5 months old, respectively) is described. In 2 the toxic solution was mistaken for a vitamin A+D preparation due to package similarity. The main clinical symptoms included restlessness, low grade fever and inflamed oral mucosa with
Pseudohyperkalemia and extreme leukocytosis.
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Two patients with chronic lymphocytic leukemia and pseudolhyperkalemia are described. Both patients had white blood cell counts exceeding 600,000 per cubic millimeter. Routine determinations of serum potassium were elevated while normal values were obtained when plasma and serum were separated
Pseudohyperkalemia occurring in a patient with chronic renal failure and polycythemia vera without severe leukocytosis or thrombocytosis.
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Pseudohyperkalemia is defined as a serum potassium concentration 0.4 mEq/l greater than the plasma concentration. The basis of this phenomenon is the release of intracellular potassium from platelets, leukocytes, or erythrocytes, commonly in the setting of extreme leukocytosis (> 10 x 10(4)/microl)
Thrombocytosis elevates serum potassium.
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Spurious elevation of the serum potassium can be seen if the platelet count exceeds 1,000 x 10(9)/L in patients with myeloproliferative disease. To see if serum potassium is increased at more modest elevations of the platelet count we studied these parameters in 283 controls and 161 patients with
Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels.
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OBJECTIVE
To report a novel cell surface autoantigen of encephalitis that is a critical regulatory subunit of the Kv4.2 potassium channels.
METHODS
Four patients with encephalitis of unclear etiology and antibodies with a similar pattern of neuropil brain immunostaining were selected for autoantigen
CSF findings in patients with voltage gated potassium channel antibody associated limbic encephalitis.
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Recently, a new subtype of limbic encephalitis (LE) has been described, serologically characterized by the presence of antibodies against voltage gated potassium channels (VGKC, to be called VGKC-LE). Only little is known about CSF findings in this new disorder. Here we report the results of 29
Predicting severity of trauma by admission white blood cell count, serum potassium level, and arterial pH.
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Traumatized patients frequently have leukocytosis, hypokalemia, and acidosis. The purpose of this study was to determine whether the admission serum potassium level (K+), white blood cell count (WBC), and arterial pH predicted the severity of injury in trauma patients. The injury severity score
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