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leukopenia/phosphatase
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[A differential cytochemical acid phosphatase granulocytogram in the study of leukopenia].
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[Neutrophil alkaline phosphatase activity in leukopenia occurring during chemotherapy].
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Alkaline phosphatase activity of the polymorphonuclear leukocyte in rapidly induced leukopenia and leukocytosis.
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Granulocyte colony-stimulating factor treatment of leucopenia during fractionated radiotherapy.
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11 patients suffering from an isolated leucopenia during fractionated radiotherapy were treated with granulocyte colony stimulating factor (G-CSF). 4 of the patients received radiotherapy alone, and 7 patients received concomitant chemotherapy. G-CSF treatment was initiated at the occurrence of
[Granulocyte alkaline phosphatase--a biomarker of chronic benzene exposure].
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In tracing the cellular population status in the peripheral blood of workers, exposed to benzene, was included and cytochemical determination of the alkaline phosphatase activity in leucocytes. This enzyme is accepted as marker of the neutrophilic granulocytes, as maturation of the cells and their
[Treatment of Paget's disease with low dose sodium etidronate (5mg/kg/day). Occurrence of reversible transient suspected leukopenia].
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27 patients with Paget's disease, from 51 to 80 years of age, were treated with etidronate disodium at a dose of 5 mg/kg/day. 70 percent of patients had multiple bone involvement. Six patients had previously been treated with diphosphonates, and nine had previously received synthetic pork or salmon
Absence of neutral protease and alkaline phosphatase in neutrophils of a case of hairy cell leukemia.
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Enzymaticaly homogeneous fractions of lymphocytes, monocytes, and neutrophils were isolated by zonal centrifugation from peripheral blood of a patient with hairy cell leukemia, or leukemic reticuloendotheliosis, LRE,(with leukopenia, neutropenia, lymphocytosis, and massive splenomegaly). To detect
Regeneration in small intestine following exposure to X-radiation and neutron beam as estimated in the light of changes in alkaline phosphatase activity and degree of 3H-thymidine incorporation into cells in intestinal crypts.
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Swiss mice were irradiated with X-rays (5, 7 and 9 Gy) and neutrons (3 and 5 Gy) determining the degree of 3H-thymidine incorporation into the cells in the intestinal crypts, alkaline phosphatase activity in intestinal homogenate and serum, and radiation-induced leucopenia. It was shown that damage
Benzene-specific increase in leukocyte alkaline phosphatase activity in rats exposed to vapors of various organic solvents.
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Female Wistar rats were exposed to various solvent vapors 8 h/d for 7 d. The leukocyte suspension and serum were prepared from peripheral blood and utilized for the determination of alkaline phosphatase (AP) activity with disodium phenyl phosphate as a substrate [leukocyte AP (LAP) and serum AP
Cordyceps sinensis health supplement enhances recovery from taxol-induced leukopenia.
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This study aimed to evaluate the ability of the health food supplement Cordyceps sinensis (CS) to ameliorate suppressive effects of chemotherapy on bone marrow function as a model for cancer treatment. Mice were treated with Taxol (17 mg/kg body wt) one day before oral administration of a hot-water
Phase I study of high dose etoposide phosphatase with filgrastim (G-CSF) in the treatment of advanced refractory malignancies.
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OBJECTIVE
To define the maximum tolerated dose of etoposide phosphate when used with G-CSF in the treatment of patients with refractory malignancies.
METHODS
Eleven patients with advanced cancer refractory to standard therapy were treated with etoposide phosphate given over 1-2 hours on three
Feasibility and effectiveness of trifluridine/tipiracil in metastatic colorectal cancer: real-life data from The Netherlands.
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BACKGROUND
The RECOURSE trial showed clinical efficacy for trifluridine/tipiracil for refractory metastatic colorectal cancer patients. We assessed the feasibility and effectiveness of trifluridine/tipiracil in daily clinical practice in The Netherlands.
METHODS
Medical records of patients from 17
Pathophysiologic and immunologic changes in a canine endotoxemia over a period of 24 hours.
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In this study, the pathophysiologic and immunologic parameters from a 24-hr of canine endotoxemia model by lipopolysaccharide (LPS) infusion were evaluated. For that, twelve healthy beagles received a continuous 24-hr IV infusion of low dose LPS (10 µg/kg/h, from Escherichia coli serotype O111:B4)
Acute Lymphoblastic Leukemia Presenting with Liver Infiltration and Severe Lactic Acidosis.
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BACKGROUND Type-B lactic acidosis is a rare complication of solid tumors and hematological malignancies. It occurs secondary to Warburg effect, when glucose metabolism in cancer cells switches from the oxidative pathway to the glycolytic pathway. Malignant lactic acidosis is a life-threatening
Chronic toxicity of nivalenol in female mice: a 2-year feeding study with Fusarium nivale Fn 2B-moulded rice.
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Groups of 42 7-wk-old female C57BL/6CrSlc SPF mice were fed diets containing 0, 6, 12 and 30 ppm nivalenol (NIV) for 2 years. Body-weight gain was reduced in all treated groups of animals and feed efficiency was reduced, significantly so, in the high-dose group. The absolute weights of the liver in
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