4 résultats
INTRODUCTION
Glucosylceramide is the condensation product of UDP-glucose and ceramide and its formation is catalysed by glucosylceramide synthase (GCS, EC 2.4.1.80).
The enzymes involved in ceramide biosynthesis are localized on the cytosolic leaflet of the endoplasmic reticulum. The biosynthesis
INTRODUCTION
Glucosylceramide is the condensation product of UDP-glucose and ceramide and its formation is catalysed by glucosylceramide synthase (GCS, EC 2.4.1.80).
The enzymes involved in ceramide biosynthesis are localized on the cytosolic leaflet of the endoplasmic reticulum. The biosynthesis
BACKGROUND OF THE INVENTION
Neuronal nicotinic acetylcholine receptors (nAChRs) serve a wide range of physiological functions and have been implicated in a number of pathological processes and pharmacological effects of nicotinic drugs. Many of the important in vivo effects of nicotine in the
BACKGROUND OF THE INVENTION
Neuronal nicotinic acetylcholine receptors (nAChRs) serve a wide range of physiological functions and have been implicated in a number of pathological processes and pharmacological effects of nicotinic drugs. Many of the important in vivo effects of nicotine in the