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Larvicidal activity of lignans and alkaloid identified in Zanthoxylum piperitum bark toward insecticide-susceptible and wild Culex pipiens pallens and Aedes aegypti.
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BACKGROUND
The yellow fever mosquito, Aedes aegypti, and the common house mosquito, Culex pipiens pallens, transmit dengue fever and West Nile virus diseases, respectively. This study was conducted to determine the toxicity of the three lignans (-)-asarinin, sesamin and
Bioactive Lignans from Zanthoxylum alatum Roxb. stem bark with cytotoxic potential.
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BACKGROUND
Zanthoxylum alatum is used in traditional medicinal systems for number of disorders like cholera, diabetes, cough, diarrhea, fever, headache, microbial infections, toothache, inflammation and cancer. The aim of the present study was to evaluate Zanthoxylum alatum stem bark for its
An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever.
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A virtual screening analysis of our library of phytochemical structures with dengue virus protein targets has been carried out using a molecular docking approach. A total of 2194 plant-derived secondary metabolites have been docked. This molecule set comprised of 290 alkaloids (68 indole alkaloids,
Saucerneol D inhibits dendritic cell activation by inducing heme oxygenase-1, but not by directly inhibiting toll-like receptor 4 signaling.
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BACKGROUND
Saururus chinensis is a medicinal plant used to treat jaundice, pneumonia, edema, fever, and several inflammatory diseases. Saucerneol D (SD), a lignan constituent of this plant, has antioxidant, anti-asthmatic, and anti-inflammatory activities. SD has been previously reported to inhibit
Comparative Metabolite Profiling of Wild and Cultivated Justicia procumbens L. Based on 1 H-NMR Spectroscopy and HPLC-DAD Analysis
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Justicia procumbens L. is known across Korea, India, China, and Taiwan as a remedy against fever, cough, sore throat, and cirrhosis of ascites. J. procumbens provides the raw material for a candidate anti-asthma drug (DW2008S) currently completing phase I clinical trials sponsored by
Phytochemistry and pharmacology of the genus Drypetes: A review.
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OBJECTIVE
Traditional medicinal use of species of the genus Drypetes is widespread in the tropical regions. The aim of this review is to systematically appraise the literature available to date on phytochemistry, ethnopharmacology, toxicology and bioactivity (in vitro and in vivo) of crude extracts
[Advances in studies on chemical constituents and pharmacological activities from plants of Symplocaceae].
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The chemical constituents and pharmacological activities on the genus of Symplocos were reviewed. Their constituents mainly included triterpenes and triterpenoid saponins, flavonoids, iridoids, lignans, alkaloids, polysaccharides and ellagic acids. A number of species among them have been used as
Transcriptome profiling of influenza A virus-infected lung epithelial (A549) cells with lariciresinol-4-β-D-glucopyranoside treatment.
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The influenza A virus is an acute contagious pathogen that affects the human respiratory system and can cause severe lung disease and even death. Lariciresinol-4-β-D-glucopyranoside is a lignan that is extracted from Isatis indigotica, which is a medicinal herb plant that was commonly applied to
Bioactive compounds from Taiwania cryptomerioides.
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Two new sesquiterpenes, 10 alpha-hydroxyamorphan-4-en-3-one (1) and 4 alpha-methylcadinane-4 alpha-methyl-1 alpha,2 alpha,10 alpha-triol (2), together with four known compounds, sesquiterpenes 10 alpha-hydroxycadinan-4-en-3-one (3) and alpha-cadinol (4), diterpene ferruginol and lignan helioxanthin,
An in-silico investigation of anti-Chagas phytochemicals.
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Over 18 million people in tropical and subtropical America are afflicted by American trypanosomiasis or Chagas disease. In humans, symptoms of the disease include fever, swelling, and heart and brain damage, usually leading to death. There is currently no effective treatment for this disease. Plant
Piper sarmentosum Roxb.: A review on its botany, traditional uses, phytochemistry, and pharmacological activities
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Ethnopharmacological relevance: Piper sarmentosum Roxb. (Piperaceae) is a traditional medicinal plant widely distributed in India, Malaysia, Thailand, and the southeastern coastal areas of China including Fujian, Guangdong, and Guizhou.
Chemical Characterization of Novel Natural Products from the Roots of Asian Rice ( Oryza sativa) that Control Adipocyte and Osteoblast Differentiation.
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Oryza sativa L. is consumed globally as a staple food, and its roots have been used as a Korean and Chinese medical supplement for protection of the stomach and lungs and for amelioration of vomiting and fever. In our continuing search for biologically effective metabolites from Korean natural
Secondary metabolites and biological properties of Gesneriaceae species.
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The family Gesneriaceae comprises ca. 150 genera and 3000 species, distributed in the tropics around the world. It is constituted of herbs, lianas, or shrubs, frequently with ornamental potential, due to the beauty of their flowers. Some species have been used in traditional medicine, mainly against
Traditional usage, phytochemistry and pharmacology of Croton sylvaticus Hochst. ex C. Krauss.
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Croton sylvaticus (C. sylvaticus) is widely used as herbal medicine by the indigenous people of tropical Africa. The potential of C. sylvaticus as herbal medicine, the phytochemistry and pharmacological properties of its parts used as herbal medicines are reviewed. The extensive literature survey
Beneficial health applications and medicinal values of Pedicularis plants: A review.
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Pedicularis plants (Orobanchaceae), popularly known as lousewort, are found in Asia, Europe, and North America, and have been used in Sowa-Rigpa, the Himalayan art of healing and a traditional system of medicine for treating various ailments in humans. A comprehensive compilation on this valuable
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