Français
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
lipoxygenase/neoplasms
Le lien est enregistré dans le presse-papiers
Page 1 de 27 résultats
Method for induction of tumor cell apoptosis with chemical inhibitors targeted to 12-lipoxygenase
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to methods for the identification and use of chemical compounds that can selectively kill tumor cells by inducing cell apoptosis. Apoptosis is a natural process for normal cells and means programmed cell death. Tumor
Use of lipoxygenase inhibitors and PPAR ligands as anti-cancer therapeutic and intervention agents
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF THE INVENTION
The present invention is in the field of the prevention and treatment of cancer. More specifically, this invention relates to the use of 5-lipoxygenase inhibitors and PPAR ligands or derivatives thereof in preventing and treating cancer.
BACKGROUND OF THE INVENTION
The
Use of lipoxygenase inhibitors as anti-cancer therapeutic and intervention agents
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF THE INVENTION
This invention is in the field of the prevention and treatment of cancer. More specifically, this invention relates to the use of 5-lipoxygenase inhibitors or derivatives thereof in preventing and treating cancer.
BACKGROUND OF THE INVENTION
Arachidonic acid (AA) is a
1,2,4-tribsubstituted benzenes as inhibitors of 15-lipoxygenase
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF THE INVENTION
The present invention provides inhibitors of the enzyme 15-lipoxygenase, pharmaceutical compositions comprising said inhibitors, and methods of treating diseases responsive to inhibition of 15-lipoxygenase.
BACKGROUND OF THE INVENTION
Hypercholesterolemia can induce monocytes
4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
BACKGROUND OF THE INVENTION
Lipoxygenases are a class of non-heme iron-containing enzymes which regio- and stereospecifically oxidize polyunsaturated fatty acid substrates such as arachidonic acid (AA) and linoleic acid (LA). (Solomon, et al. Chem. Biol. 1997, 4, 795-808; Brash, J. Biol. Chem. 1999,
Method for inhibiting 15-lipoxygenase with fermented Glycine max (L.) extract
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
RELATED APPLICATION(S)
The present application is a continuation in part application of U.S. patent application Ser. No. 09/812,579, filed on Mar. 21, 2001, now abandoned.
TECHNICAL FIELD
This invention relates to a use of a fermented Glycine max (L.) extract in inhibiting 15-lipoxygenase,
5-lipoxygenase inhibitors
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF THE INVENTION
The present invention relates to 5-lipoxygenase inhibitors. Compounds disclosed herein can be useful in the treatment of bronchial asthma , chronic obstructive pulmonary disorder, arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory
Inhibitors of human 12/15-lipoxygenase
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
TECHNICAL FIELD
The present invention relates generally to inhibition of 12/15-lipoxygenase, treatment of a condition involving 12/15-lipoxygenase including, but not limited to, strokes, periventricular leukomalacia, cardiac arrest with resuscitation, atherosclerosis, Parkinson's disease,
Human leukocyte 12-lipoxygenase and its role in the pathogenesis of disease states
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
TECHNICAL FIELD
This invention pertains to a human leucocyte type of 12-LO and its role in the pathogenesis of several major disease states.
ABBREVIATIONS AA = Arachidonic acid AII = Angiotensin II EGF = Epidermal Growth Factor EN = Fibronectin GAPDH = Glyceraldehyde-3-phosphate dehydrogenase GF =
Human leukocutye 12-lipoxygenase and its role in the pathogenesis of disease states
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
TECHNICAL FIELD
This invention pertains to a human leucocyte type of 12-LO and its role in the pathogenesis of several major disease states.
ABBREVIATIONS AA=Arachidonic acid AII=Angiotensin II EGF=Epidermal Growth Factor FN=Fibronectin GAPDH=Glyceraldehyde-3-phosphate dehydrogenase GF=Growth Factor
Human leukocyte 12-lipoxygenase and its role in the pathogenesis of disease states
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
TECHNICAL FIELD
This invention pertains to a human leucocyte type of 12-LO and its role in the pathogenesis of several major disease states.
ABBREVIATIONS AA = Arachidonic acid AII = Angiotensin II EGF = Epidermal Growth Factor FN = Fibronectin GAPDH = Glyceraldehyde-3-phosphate dehydrogenase GF =
Formulation of dual cycloxygenase (COX) and lipoxygenase (LOX) inhibitors for mammal skin care
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF THE INVENTION
This invention relates generally to a method for the prevention and treatment of diseases and conditions mediated by cyclooxygenase (COX) and lipoxygenase (LOX). Specifically, the present invention relates to a novel composition of matter comprised of a mixture of a blend of
Formulation of dual cycloxygenase (COX) and lipoxygenase (LOX) inhibitors for mammal skin care
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF THE INVENTION
This invention relates generally to a method for the prevention and treatment of diseases and conditions mediated by cyclooxygenase (COX) and lipoxygenase (LOX). Specifically, the present invention relates to a novel composition of matter comprised of a mixture of a blend of
Quinazolinone-based oncogenic-RAS-selective lethal compounds and their use
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF INVENTION
The present invention provides, inter alia, quinazolinone-based oncogenic-RAS-selective lethal compounds and compositions containing such compounds. Methods for using such compounds or compositions are also provided.
BACKGROUND OF THE INVENTION
Synthetic lethality describes a
Carbonyl erastin analogs and their use
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
FIELD OF INVENTION
The present invention provides, inter alia, carbonyl erastin analogs and compositions containing such compounds. Methods for using such compounds or compositions are also provided.
BACKGROUND OF THE INVENTION
Synthetic lethality describes a genetic interaction in which
La base de données d'herbes médicinales la plus complète soutenue par la science
- Fonctionne en 55 langues
- Cures à base de plantes soutenues par la science
- Reconnaissance des herbes par image
- Carte GPS interactive - étiquetez les herbes sur place (à venir)
- Lisez les publications scientifiques liées à votre recherche
- Rechercher les herbes médicinales par leurs effets
- Organisez vos intérêts et restez à jour avec les nouvelles recherches, essais cliniques et brevets
Tapez un symptôme ou une maladie et lisez des informations sur les herbes qui pourraient aider, tapez une herbe et voyez les maladies et symptômes contre lesquels elle est utilisée.
* Toutes les informations sont basées sur des recherches scientifiques publiées
