Allergy

prerseasonal course of SCIT - three years

Purethal

Purethal -placebo

Grass Pollen Subcutaneous Immunotherapy in Elderly Patients

Grass Pollen Subcutaneous Immunotherapy: a Double-blind, Placebo-controlled Study in Elderly Patients With an Allergy to Grass Pollen

The prime outcome measure was the area under the curve (AUC) for combined symptom and medication score (SMS)

Evaluation quantities of drugs based on patient diary.

The local reactions were assessed at 30 min after injection and measured in cm.

The systemic reaction were assesed after injection according EAACI criteria.

Andrzej Bozek

Andrzej Bozek Assistant Professor, Director of Research

Medical University of Silesia

A sublingual allergen immunotherapy tablet (Oralair) containing: 300 index of reactivity (IR) of 5 grass pollen allergen extracts:perennial ryegrass (Lolium perenne), meadow grass (Poa pratensis), timothy grass (Phleum pratense), cocksfoot (Dactylis glomerata) and sweet vernal grass (Anthoxanthum odoratum) in an open label fashion administered for 4 months prior to the pollen season.

Standard medical therapy: oral antihistamines AND/OR nasal steroids AND/OR nasal antihistamines

Allergic Rhinitis

Grass pollen sublingual immunotherapy tablet

Control

Department of Allergy, Immunology and Respiratory Medicine, The Alfred Hospital- Bayside Health

Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis

Immunological Mechanisms of Oralair® (5 Grass Mix Sublingual Allergen Immunotherapy Tablet) in Patients With Seasonal Allergic Rhinitis

Bayside Health

Allergic Rhinoconjunctivitis

Sublingual. 2 drops/daily 1000 DPP/ml 2 years

Grass pollen allergenic extract (L. perenne-C. dactylon )

Sublingual. 2 drops/daily 10000 DPP/ml 2 years

placebo

Allergy Unit, UCT Lung Institute

Efficacy-safety Study of Sublingual Immunotherapy With Depigmented-polymerized Pollen Extracts to Treat Rhinoconjunctivitis

A Randomised Double Blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Sublingual Immunotherapy With a Depigmented and Polymerized Grass Pollen Extracts in Patients Suffering From Allergic Rhinoconjunctivitis.

lolium perenne/hypersensibilité

Grass Pollen Subcutaneous Immunotherapy in Elderly Patients

Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis

Efficacy-safety Study of Sublingual Immunotherapy With Depigmented-polymerized Pollen Extracts to Treat Rhinoconjunctivitis

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