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lung neoplasms/protease

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Methods for the early diagnosis of ovarian, breast and lung cancer

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BACKGROUND OF THE INVENTION 1. Field of the Invention Generally, the present invention relates to the fields of molecular biology and medicine. More specifically, the present invention is in the field of ovarian and other cancer diagnosis. 2. Background of the Invention To date, ovarian cancer

Compounds and methods for treating cancer

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BACKGROUND OF THE INVENTION Advanced non-small cell lung cancer (NSCLC) is the most common cause of cancer death for both men and women in the United States. In 2005 it is estimated that there will be over 170,000 new cases of NSCLC. Most patients are diagnosed with advanced disease and the median

Compounds and methods for treating cancer

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BACKGROUND OF THE INVENTION Advanced non-small cell lung cancer (NSCLC) is the most common cause of cancer death for both men and women in the United States. In 2005 it is estimated that there will be over 170,000 new cases of NSCLC. Most patients are diagnosed with advanced disease and the median

Non-cytotoxic fusion proteins comprising EGF muteins

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The present invention relates to non-cytotoxic fusion proteins, and to the use thereof as therapeutics for suppressing conditions such as mucus hypersecretion, inflammation, neuroendocrine disorders, and neuroendocrine tumours. Non-cytotoxic proteases are a discrete group of proteases, which act on
REFERENCE TO SEQUENCE LISTING This application contains a Sequence Listing submitted as an electronic text file named "14fpo.sub.--03.sub.--009_ST25.txt", having a size in bytes of 2 KB, and created on Apr. 18, 2014. The information contained in this electronic file is hereby incorporated by

Polypeptides that bind to and inhibit secretion from growth hormone secreting cells

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The present invention relates to the suppression of the growth, maintenance, and progression of common cancers, in particular colorectal, prostate, breast and lung cancers. Colorectal cancer is the third most common cancer in both men and women in the United States, according to the World Health

Suppression of prostate cancer using a targeted clostridial neurotoxin

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Pursuant to the provisions of 37 C.F.R. .sctn. 1.52(e)(5), the sequence listing text file named 98374_Seq_Listing.txt, created on Apr. 9, 2014 and having a size of 652,334 bytes, and which is being submitted herewith, is incorporated by reference herein in its entirety. The present invention relates

Anti-metalloprotease antibody for diagnosis and treatment of cancers

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INCORPORATION-BY-REFERENCE OF MATERIAL ELECTRONICALLY SUBMITTED Incorporated by reference in its entirety herein is a computer-readable nucleotide/amino acid sequence listing su currently herewith and identified as follows: One 8,709 Byte SCII (Text) filed named "726179_ST25.TXT," created Feb. 26,

2-aminopyrimidine compound and pharmaceutical composition and use thereof

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a national stage filing under 35 U.S.C. .sctn. 371 of international application PCT/CN2015/094954, filed Nov. 18, 2015, which claims priority to Chinese Application No. 201410682756.9, filed Nov. 24, 2014, the disclosures of each of which
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