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macular degeneration/obésité
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Administration of nicotinamide mononucleotide in the treatment of disease
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INTRODUCTION
Age-related obesity is a health-related problem for which new treatments and methods of ameliorating, mitigating, or reversing are needed. U.S. Pat. No. 8,268,575 to Imai, S., et al. asserts that "Chemical effectors for mammalian NAD biosynthesis can mediate a variety of anti-aging
Administration of nicotinamide mononucleotide in the treatment of disease
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INTRODUCTION
Age-related obesity is a health-related problem for which new treatments and methods of ameliorating, mitigating, or reversing are needed. U.S. Pat. No. 8,268,575 to Imai, S., et al. asserts that "Chemical effectors for mammalian NAD biosynthesis can mediate a variety of anti-aging
Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids
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FIELD OF THE INVENTION
The present invention concerns the preparation and uses of adamantanamines (e.g. memantine, amantadine and rimantadine) and neramexane(s) salts of thiomolybdic acids and thiotungstic acids. Their pharmaceutical compositions incorporate two complementary, bioavailable
Deuterium-enriched pyridinonecarboxamides and derivatives
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SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinonecarboxamides and derivatives thereof of formula 1,
##STR00002## Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
Deuterium-enriched alkyl sulfonamides and uses thereof
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FIELD OF THE INVENTION
The present invention generally relates to deuterium-enriched N-acetylamino-(piperazinyl)-butyl)-alkylsulfonamides of formula 1, their pharmaceutically acceptable salts, synthesis and methods of use thereof. These compounds are 5-HT (serotonin) receptor modulators more
Solid oral formulation of fenretinide
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TECHNICAL FIELD
The present invention generally relates to pharmaceutical formulations, and more specifically to oral pharmaceutical compositions comprising the active ingredient fenretinide or analogs thereof.
BACKGROUND ART
Fenretinide (all-trans-N-(4-hydroxyphenyl) retinamide; also referred to as
Solid oral formulation of fenretinide
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TECHNICAL FIELD
The present invention generally relates to pharmaceutical formulations, and more specifically to oral pharmaceutical compositions comprising the active ingredient fenretinide or analogs thereof.
BACKGROUND ART
Fenretinide (all-trans-N-(4-hydroxyphenyl) retinamide; also referred to as
Nitrogen heterocycle biaryls for osteoporosis and other diseases
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FIELD OF THE INVENTION
The invention relates to a genus of nitrogen heterocycle biaryls having a carboxylate terminus. The nitrogen heterocycle biaryls are useful for treating endometriosis, osteoporosis, restenosis following angioplasty, rheumatoid arthritis, cancer, macular degeneration and
Chemical inhibitors of inhibitors of differentiation
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TECHNICAL FIELD
The present invention relates to compositions and methods for controlling cellular determination and differentiation in mammalian subjects. More specifically, the invention relates to compositions and methods for inhibiting inhibitors of differentiation (Id), particularly inhibiting
Aminothiazole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2010/067383 filed Oct. 4, 2010, claiming priority based on Japanese Patent Application No. 2009-240008 filed Oct. 19, 2009, the contents of all of which are incorporated herein by
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