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noradrenaline/fièvre

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Nitric oxide mediates noradrenaline-induced hypothermic responses and opposes prostaglandin E2-induced fever in the rostromedial preoptic area.

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Noradrenaline (NA) microinjected into the rostromedial preoptic area (POA) elicits heat loss responses and opposes prostaglandin E(2)-induced fever. Here, I tested the hypothesis that local synthesis and release of nitric oxide (NO) mediates the NA-induced effects. The unilateral microinjection of

Contrasting roles of 5-hydroxytryptamine and noradrenaline in fever in rats.

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1. We have investigated the effects of endogenous monoamine depletion on the development of fever in rats. 2. Fever was produced in rats by a single intraperitoneal injection of Salmonella typhosa endotoxin or leucocyte pyrogen manufactured from ox blood. 3. Depletion of brain 5-hydroxytryptamine
We have measured the effects of ephedrine, adrenaline, noradrenaline and isoprenaline on halothane-induced contractures in muscle biopsies from patients potentially susceptible to malignant hyperthermia (MH). At concentrations of 4-24 mmol litre-1, ephedrine induced in vitro contractures in

The effect of prazosin pretreatment on hyperthermia produced by noradrenaline in rabbits.

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1. Hyperthermia produced by noradrenaline (NA) was accompanied by increased metabolic rate and vasoconstriction of ear skin vessels and a fall in evaporation heat loss. 2. Prazosin (PRA), administered as a single injection, decreased of hyperthermia elicited by NA mainly of attenuation the processes

The influence of prazosin on E. coli lipopolysaccharide-induced fever and noradrenaline hyperthermia.

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We investigated the effect of prazosin on experimental fever induced by E. coli lipopolysaccharide (LPS) and on noradrenaline hyperthermia in the rabbit. LPS and prazosin were administered iv and ivc, noradrenaline was administered only iv. Prazosin inhibited both LPS fever and noradrenaline

[Enhancement of antitumor effect of MMC on Walker 256 by intra-arterial administration of noradrenaline in hyperthermia].

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We performed a study of hyperthermia while injecting 0.05% of Noradrenaline following MMC for 10 minutes into the feeding artery of Walker-256 carcinosarcomas implanted 6 days earlier into the s.c. dorsum side of hindpaw of Wistar rats. The tumor growth rates on the 6th day after treatment by
Wistar rats were injected sc, with cells from Walker-256, which is resistant to hyperthermia. When hyperthermia was achieved by immersing the tumor at 44 degrees C for 60 minutes after injecting MMC (0.5 mg/kg), tumor growth was markedly suppressed in D-8 group, which formed many tumor vessels, but

The effect of highly selective inhibitors of the uptake of noradrenaline or 5-hydroxytryptamine on TRH-induced hyperthermia in mice.

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Well established as supposed antidepressant drugs, desipramine (1.25-5 mg/kg), nisoxetine (0.625-2.5 mg/kg) and clomipramine (1.25-5 mg/kg) but not fluoxetine (2.5-40 mg/kg) or citalopram (2.5-40 mg/kg) dose-dependently potentiated TRH (40 mg/kg)-induced hyperthermia in mice. Alpha-adrenergic

Blockade of dopamine, but not noradrenaline, transporters produces hyperthermia in rats that lack serotonin transporters.

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To investigate whether life-long disturbed serotonin neurotransmission may result in adaptive changes of dopaminergic and noradrenergic systems, effects of drugs on stress-induced hyperthermia were studied in serotonin transporter knockout rats. The noradrenalin transporter blocker atomoxetine was

Pyrogen and prostaglandin fever in the rabbit-II: Effects of noradrenaline depletion and adrenergic receptor blockade.

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Proceedings: A role for noradrenaline and cyclic AMP in prostaglandin E1 Fever.

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Immobilization stress induced hyperthermia in rats: possible role of noradrenaline.

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[Neuronal uptake of 3H-noradrenaline by isolated organs of rats under hyperthermia].

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The role of noradrenaline in the rabbit brain during pyrogen-induced fever.

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