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Acute toxicity studies of aluminium compounds: antidotal efficacy of several chelating agents.
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Four aluminum compounds--nitrate, chloride, sulphate and bromide--were administered orally and intraperitoneally to rats and mice. The LD50-values (14 days) were determined. The majority of deaths occurring during the first four days. The clinical and physical signs appearing after intoxication
Determination of haemoglobin in gastric aspirates.
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The haemoglobin content of gastric aspirates can be quantitated by conversion of non-fluorescent haem to fluorescent porphyrins by heating gastric aspirates with oxalic acid and ferrous sulphate. Recovery of haemoglobin added to gastric aspirates was 92 +/- 9%, variation coefficient, n = 52, day to
Comparison of qualitative and quantitative blood determinations in stools of healthy persons and patients with colorectal tumours.
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The possibility of using fecal blood determination for early diagnosis of colorectal cancer is based on the fact that in most cases bleeding from the tumour occurs early in the asymptomatic phase of the disease. The qualitative Haemoccult test is now regarded as most suitable for screening. The test
Localized deposition of calcium oxalate around a pulmonary Aspergillus niger fungus ball.
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A case of pulmonary Aspergillus niger fungus ball is presented. Crystals of calcium oxalate, presumably derived from oxalic acid produced by the fungus, were deposited in tissues around the fungus ball. The crystals were identified by x-ray diffraction analysis. Histochemical technics for the
[Change of joint synovial clearance speed in experimental arthritis].
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The radio activity of 131I-Hippuran injected into the knees was investigated in rabbits and found to decrease with passage of the time. The disappearance curve was monoexponential and the disappearance rate was able to be obtained by a biological half life (T 1/2). This evidence showed that
Burden and etiopathogenesis of acute kidney injury in the tropics.
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Acute kidney injury (AKI) is prevalent and is associated with high morbidity and mortality globally. The epidemiology differs remarkably between developing and developed economies. Infections, diarrheal illnesses, obstetric causes and nephrotoxins are very rampant in the tropics. Even though the
[Determination of ascorbic and dehydroascorbic acid concentration using HPLC method in smokers with stable coronary artery disease scheduled for coronary artery bypass grafting (CABG)].
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Ascorbic acid is a vitamin soluble in water and its deficiency in human body causes scurvy. Its symptoms in adults are gingivitis, susceptibility of blood vessels to damage and bleeding, changes in bones and cartilage and retarded wound healing. Ascorbic acid is necessary in redox processes taking
Dosimetry considerations in the enhanced sensitivity of male Wistar rats to chronic ethylene glycol-induced nephrotoxicity.
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Male Wistar rats have been shown to be the most sensitive sex, strain and species to ethylene glycol-induced nephrotoxicity in subchronic studies. A chronic toxicity and dosimetry study was therefore conducted in male Wistar rats administered ethylene glycol via the diet at 0, 50, 150, 300, or 400
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