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pancreatitis/obésité
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Obesity: a prognostic factor of severity in acute pancreatitis.
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This study was conducted to assess the prognostic value of obesity in acute pancreatitis and to determine the role played by obesity-associated diseases in the course of the disease. We prospectively studied 49 patients with acute pancreatitis who were divided into three groups according to their
Does the presence of obesity and/or metabolic syndrome affect the course of acute pancreatitis?: A prospective study.
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OBJECTIVE
The incidence of acute pancreatitis (AP) is rising with increased prevalence of obesity, which exacerbates pancreatic injury. Metabolic syndrome (MS) is defined as a cluster condition of cardiovascular risk factors, including hyperglycemia, dyslipidemia, hypertension, and central obesity.
Fatal hemorrhagic-necrotizing pancreatitis associated with pancreatic and hepatic lipidosis in an obese Asian palm civet (Paradoxurus hermaphroditus).
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Asian palm civets (Paradoxurus hermaphroditus), or toddy cats, belong to the family Viverridae. Little is known about the pathology of these animals and few articles have been published, mainly concerning their important role as wild reservoir hosts for severe infectious diseases of domestic animals
Perforated appendicitis masquerading as acute pancreatitis in a morbidly obese patient.
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Diagnosis and treatment of common conditions in morbidly obese patients still pose a challenge to physicians and surgeons. Sometimes too much reliance is put on investigations that can lead to a misdiagnosis. This case demonstrates an obese woman admitted under the medical team with a presumed
Influence of obesity on the severity and clinical outcome of acute pancreatitis.
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OBJECTIVE
Obesity tends to be associated with increased mortality and morbidity in acute pancreatitis. However, in Asian populations, higher morbidity and mortality have been reported in patients with low body mass indexes (BMIs). This study was undertaken to evaluate the relation between obesity
Pancreatitis following intestinal bypass for obesity.
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Three out of 24 patients undergoing intestinal bypass in the treatment of morbid obesity have developed acute pancreatitis in the postoperative period. All three had undergone end-to-end jejunoileal bypass. This serious postoperative complication has been infrequently recorded. Its significance and
The association between obesity and outcomes in acute pancreatitis: an individual patient data meta-analysis.
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OBJECTIVE
There are data to suggest that obesity is associated with local and systemic complications as well as mortality in acute pancreatitis (AP). Cohort studies to date, however, have shown conflicting results from mostly unadjusted analyses. Therefore, we performed an individual patient data
New wine into old wineskins: PGC-1α and NF-κB in obesity and acute pancreatitis.
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Obesity and acute pancreatitis are both proinflammatory conditions. Importantly, obesity increases severity in acute pancreatitis by enhancing inflammation. In a recent issue of The Journal of Pathology, Pérez and Ruiz-Pérez et al connected obesity and pancreatitis for the first time, through the
Obesity correlates with early hyperglycemia in patients with acute pancreatitis who developed organ failure.
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OBJECTIVE
Early hyperglycemia in acute pancreatitis (AP) is a prognostic sign of severe attack. Obesity, another risk factor for severe AP, is associated with impaired glucose regulation. We hypothesized that obesity is related to early hyperglycemia in patients with severe AP.
METHODS
Forty-four
Features of the course of acute pancreatitis in patients with obesity.
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Implementation of the Asia-Pacific guidelines of obesity classification on the APACHE-O scoring system and its role in the prediction of outcomes of acute pancreatitis: a study from India.
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OBJECTIVE
We studied the role of obesity and the Acute Physiology and Chronic Health Evaluation (APACHE) O score in predicting the outcome in patients with acute pancreatitis (AP) using the Asia-Pacific obesity classification.
METHODS
Two hundred eighty AP patients were classified into three
Leptin alleviates intestinal mucosal barrier injury and inflammation in obese mice with acute pancreatitis.
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OBJECTIVE
Obesity is an independent risk factor for severe acute pancreatitis (AP). Leptin plays an important role in energy homeostasis. It has been reported that leptin might also participate in the regulation of the intestinal mucosal barrier and inflammatory response. This study aimed to
Obesity and treatment of diabetes with glyburide may both be risk factors for acute pancreatitis.
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OBJECTIVE
To evaluate risk factors, notably drugs, for acute pancreatitis.
METHODS
A population-based case-control study was conducted of 1.4 million inhabitants, aged 20-85 years, of four regions in Sweden between 1 January 1995 and 31 May 1998. A total of 462 case subjects were hospitalized in
A murine model of obesity implicates the adipokine milieu in the pathogenesis of severe acute pancreatitis.
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Obesity is clearly an independent risk factor for increased severity of acute pancreatitis (AP), although the mechanisms underlying this association are unknown. Adipokines (including leptin and adiponectin) are pleiotropic molecules produced by adipocytes that are important regulators of the
Experimental evidence of obesity as a risk factor for severe acute pancreatitis.
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The incidence of acute pancreatitis, an inflammation of the pancreas, is increasing worldwide. Pancreatic injury is mild in 80%-90% of patients who recover without complications. The remaining patients may develop a severe disease with local complications such as acinar cell necrosis, abscess and
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