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pentose/hémorragie
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13 résultats
Modification of cardio-vascular responses to hemorrhage by induced hyperosmolality in the rat.
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Starved rats sedated with a neurolept analgesic were subjected to hemorrhagic hypotension while receiving infusions of iso-osmolar and hyperosmolar solutions. The hemorrhage model used resulted in similar residual blood volumes and hematocrits in all groups. The non-metabolizable pentose, xylose,
The Metabolopathy of Tissue Injury, Hemorrhagic Shock and Resuscitation in a Rat Model.
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BACKGROUND
The metabolic consequences of trauma induce significant clinical pathology. In this study, we evaluate the independent, metabolic contributions of tissue injury (TI) and combined tissue injury and hemorrhagic shock (TI/HS) using mass spectrometry (MS) metabolomics in a controlled animal
Metabolomics analysis of gut barrier dysfunction in a trauma-hemorrhagic shock rat model.
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Intestinal barrier dysfunction has been implicated in the development of multiorgan dysfunction syndrome (MODS) caused by the trauma-hemorrhagic shock (THS). However, the mechanisms underlying THS-induced gut barrier injury are still poorly understood. In this study, we used the metabolomics
The pathology and biochemistry of paraquat.
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After the administration of paraquat to rats the lung is the organ most severely damaged. The pathology in the lung can be divided into two distinct phases: (1) a destruction phase lasting a few days with damage to the type I and type II alveolar epithelial cells, oedema and haemorrhage (most of the
Biosynthesis of an antiviral compound using a stabilized phosphopentomutase by multipoint covalent immobilization.
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Ribavirin is a synthetic guanosine analogue with a broad-spectrum of antiviral activity. It is clinically effective against several viruses, such as respiratory syncytial virus, several hemorrhagic fever viruses and HCV when combined with pegylated interferon-α. Phosphopentomutase (PPM) catalyzes
[Enzyme activity in the normal atrioventricular node and in the bundle of His in young children].
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The authors examined by histochemical methods the atrioventricular node and the bundle of His in five infants who died from unnatural deaths and in a four-and-half-year-old child who died immediately following haemorrhagic infarction of the gut. Both structures differed, similarly as in adult age,
Small-Scale Perfusion Bioreactor of Red Blood Cells for Dynamic Studies of Cellular Pathways: Proof-of-Concept.
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To date, the development of bioreactors for the study of red blood cells (RBCs, daily transfused in the case of disease or hemorrhage) has focused on hematopoietic stem cells. Despite the fact that mature RBCs are enucleated and do not expand, they possess complex cellular and metabolic pathways, as
Transaldolase deficiency: report of 12 new cases and further delineation of the phenotype.
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OBJECTIVE
Transaldolase deficiency is a recently described inborn error of pentose phosphate pathway. We conducted this study to further delineate the associated phenotype.
RESULTS
We report on 12 new cases representing six families with this metabolic defect that were observed over an 8 year span.
Transaldolase deficiency in two new patients with a relative mild phenotype.
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Transaldolase (TALDO) deficiency is a recently described inborn error of metabolism of the pentose phosphate pathway that so far has been diagnosed in only eight patients. In this article, we report the clinical course and biochemical findings of two newly identified patients with TALDO
Carbohydrate metabolism and the temporal occurrence of a serotonin-like indole in the male and female reproductive tract and its relationship with PGF and infertility: a review.
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Both in the male and in the female reproductive tract glucose can be converted via either the pentose pathway or the sorbitol pathway. It is shown that a disturbed carbohydrate metabolism can lead to infertility, i.e. in the cow and in the bull semen. Evidence is provided that the serotonin-like
Clinical and molecular characteristics of two transaldolase-deficient patients.
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Transaldolase (TALDO) deficiency is a rare metabolic disease in the pentose phosphate pathway, which manifests as a severe, early-onset multisystem disease. The body fluids of affected patients contain increased polyol concentrations and seven-carbon chain carbohydrates. We report the molecular and
Erythritol: Another C4 Platform Chemical in Biomass Refinery.
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The potential of erythritol as a platform chemical in biomass refinery is discussed in terms of erythritol production and utilization. Regarding erythritol production, fermentation of sugar or starch has been already commercialized. The shift of the carbon source from glucose to inexpensive inedible
Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel.
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Arctic ground squirrels provide a unique model to investigate metabolic responses to hibernation in mammals. During winter months these rodents are exposed to severe hypothermia, prolonged fasting, and hypoxemia. In the light of their role in oxygen transport/off-loading and owing to the absence of
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