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phytomenadione/hémorragie
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15 résultats
Oral versus intramuscular phytomenadione: safety and efficacy compared.
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Oral and intramuscular phytomenadione (vitamin K1) prophylaxis became an issue following the report of a potential carcinogenic effect of intramuscular but not oral phytomenadione prophylaxis. There is increasing evidence, however, that oral phytomenadione prophylaxis is less effective for the
[Post-tonsillectomy haemorrhage treatment with activated factor VII].
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Tonsillectomy is a common procedure in otorhinolaryngology and postoperative haemorrhage is a well-known complication. In this case, a 34 year-old male with obstructive sleep apnoea and no coagulation defects was operated; 30 minutes after the operation he presented with primary post operative
Vitamin K deficiency bleeding and early infant male circumcision in Africa.
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BACKGROUND
Early infant (1-60 days of life) male circumcision is being trialed in Africa as a human immunodeficiency virus prevention strategy. Postcircumcision bleeding is particularly concerning where most infants are breastfed, and thus these infants are at increased risk of vitamin K deficiency
Phytomenadione or menadiol in the management of an elevated international normalized ratio (prothrombin time).
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OBJECTIVE
To evaluate the efficacy of oral menadiol compared to intravenous phytomenadione when correcting coagulopathies associated with cholestasis.
METHODS
A total of 26 patients with cholestasis and an international normalized ratio (prothrombin time) greater than 1.2, were randomized to receive
Superwarfarin Exposure: An Important Uncommon Cause of Painless Bleeding.
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Painless bleeding in a patient presenting from the community with elevated coagulation studies rarely makes the physicians suspect superwarfarin or rodenticide poisoning. Although a significant number of superwarfarin exposure cases are diagnosed every year, we believe there appears to be delay in
[Possible potentiation of phenprocoumon by clarithromycin and roxithromycin].
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Two patients, a women of 70 and a man of 75 years old, who were using phenprocoumon chronically, and were monitored by a regional thrombosis service, received a macrolide antibiotic, clarithromycin and roxithromycin respectively, for an airway infection. Both patients developed a serious increase in
A review of vitamin K, epilepsy and pregnancy.
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Based on a case history of fetal haemorrhage due to maternal antiepileptic treatment and a review of 40 previously described similar cases, it is recommended that epileptic mothers receive vitamin K tablets throughout the month before delivery and intravenously during labour. It is further
Weekly oral vitamin K prophylaxis in Denmark.
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OBJECTIVE
To evaluate oral vitamin K prophylaxis at birth by giving 2 mg phytomenadione, followed by weekly oral vitamin K prophylaxis; 1 mg was administered by the parents until 3 mo of age.
METHODS
A total of 507850 live babies were born in Denmark during the study period, November 1992 to June
Treatment of epilepsy in pregnancy.
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Pregnant women with epilepsy constitute 0.5% of all pregnancies. Proper seizure control is the primary goal in treating women with epilepsy. The commonly used anticonvulsants are established human teratogens. Factors such as epilepsy, anticonvulsant-induced teratogenicity, patient's genetic
Use of oral anticoagulants in older patients.
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Recently published American and British guidelines have comprehensively reviewed the indications for long term anticoagulation. The best evidence currently available supports the use of long term oral anticoagulants in patients with nonvalvular atrial fibrillation (NVAF), venous thromboembolic
Hepatitis and cholestasis in infancy: clinical and nutritional aspects.
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A major complication of cholestasis is fat malabsorption related to decreased intestinal bile acids, which leads to malnutrition and fat-soluble vitamin deficiency. The impaired excretion of bile acids leads to a low intraluminal micellar concentration that causes long-chain triglyceride lipolysis
Six years' experience of prophylactic oral vitamin K.
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OBJECTIVE
The ability of oral vitamin K to eliminate all risk of vitamin K deficiency bleeding during the first three months of life was studied.
METHODS
Babies (n=182,000) in the north of England judged well enough to be offered milk within 12 hours of birth were given 1 mg of phytomenadione
Current concepts and controversies in the use of vitamin K.
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Vitamin K is a fat-soluble vitamin crucial to the production of many proteins involved with the coagulation process. It is integral in the synthesis of coagulants (factors II, VII, IX and X) and anticoagulants (proteins C and S). It is generally recognised that routine administration of vitamin K
The use of vitamin K in patients on anticoagulant therapy: a practical guide.
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Anticoagulation with antivitamin K (AVK) is very effective for primary and secondary prevention of thromboembolic events. However, questions persist about the risks and management of over-anticoagulation. For reversal of excessive anticoagulation by warfarin, AVK withdrawal, oral or parenteral
Anticoagulant rodenticides.
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Anticoagulant pesticides are used widely in agricultural and urban rodent control. The emergence of warfarin-resistant strains of rats led to the introduction of a new group of anticoagulant rodenticides variously referred to as 'superwarfarins', 'single dose' or 'long-acting'. This group includes
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