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Urinary polyamines as prostate cancer detection biomarkers
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FIELD OF THE INVENTION
The present disclosure relates to methods for the detection and quantization of urinary polyamines and compositions for use therein. The methods and compositions described herein are useful in diagnosis of prostate cancer in patient.
BACKGROUND OF THE INVENTION
Prostate cancer
Polyamine compounds and compositions for use in conjunction with cancer therapy
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FIELD OF THE INVENTION
The present invention relates to the field of cancer therapy. In particular, the invention provides novel polyamine compounds and pharmaceutical compositions for reducing or preventing toxic side effects of radiotherapy and cancer chemotherapeutic agents.
BACKGROUND OF THE
Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
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STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable.
TECHNICAL FIELD
This invention is directed to cycloalkyl-substituted polyamine analog compounds, particularly cyclopropyl-containing polyamine analog compounds, useful as chemotherapy treatments in cancer and
Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
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TECHNICAL FIELD
This invention is directed to cycloalkyl-substituted polyamine analog compounds, particularly cyclopropyl-containing polyamine analog compounds, useful as chemotherapy treatments in cancer and other diseases caused by abnormal cell proliferation, as well as improved methods for
Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
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STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable.
TECHNICAL FIELD
This invention is directed to cycloalkyl-substituted polyamine analog compounds, particularly cyclopropyl-containing polyamine analog compounds, useful as chemotherapy treatments in cancer and
Fluorescent derivatives of polyamines, method for preparing same and applications thereof as diagnosis tools in the treatment of cancerous tumors
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The marking of biomolecules and the follow-up of biological phenomena require the designing of fluorescent probes which have become indispensable tools for structural and functional studies of biological media.
A fluorescent probe is a conjugated molecule, consisting of a fluorophore or fluorochrome
Predictive markers for polyamine inhibitor cancer therapies
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BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of cancer biology and medicine. More particularly, it concerns methods for the diagnosis, prevention, and treatment of carcinomas and risk factors thereof.
II. Description of Related
Polyamine transporter selective compounds as anti-cancer agents
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FIELD OF THE INVENTION
The present invention relates to the field of cancer treatment and, more particularly, to polyamines which, due to their special structure, preferentially enter cells having an upregulated polyamine transport system.
BACKGROUND OF THE INVENTION
Polyamines are essential growth
Polyamine transporter selective compounds as anti cancer agents
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FIELD OF THE INVENTION
The present invention relates to the field of cancer treatment and, more particularly, to polyamines which, due to their special structure, preferentially enter cells having an upregulated polyamine transport system.
BACKGROUND OF THE INVENTION
Polyamines are essential growth
Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
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TECHNICAL FIELD
This invention pertains to polyamine compounds, including polyamine/guanidine and polyamine/biguanide compounds, useful for treatment of cancer and/or parasitic infections, and for inhibition of lysine-specific demethylase.
BACKGROUND
Polyamines are found in both eukaryotic and
Porphyrin-polyamine conjugates for cancer therapy
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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable.
REFERENCE TO AN APPENDIX
Not applicable.
TECHNICAL FIELD
This invention relates to porphyrin-polyamine conjugate compounds used for treatment of cancer and other diseases.
BACKGROUND OF THE INVENTION
Cancer is the third
Polyamine conjugates as selective NMDA inhibitors and anti-cancer drugs
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FIELD OF INVENTION
This invention relates to polyamine compounds and more particularly to tetraamine derivatives and their use as N-Methyl-D-Aspartate (NMDA) inhibitors for therapeutic treatment of neurodegenerative disorders, such as stroke, Alzheimer's disease, other neurodegenerative disorders,
Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
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STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable
TECHNICAL FIELD
This invention relates to therapeutic compositions in which a cytostatic or cytocidal compound, such as a polyamine analog or a quinone, is conjugated to a polypeptide recognized and cleaved by
Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
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STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable
TECHNICAL FIELD
This invention relates to therapeutic compositions in which a cytostatic or cytocidal compound, such as a polyamine analog or a quinone, is conjugated to a polypeptide recognized and cleaved by
Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
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FIELD OF THE INVENTION
The present invention relates to the field of cancer therapy. In particular, the invention provides novel compositions and methods for reducing or preventing toxic side effects of radiotherapy and cancer chemotherapeutic agents using polyamine effector molecules locally
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