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Ultrastructural examination of corneal epithelium of spontaneously obese, hyperglycemic rats.

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OBJECTIVE Otsuka Long-Evans Tokushima fatty (OLETF) rats spontaneously become obese and hyperglycemic with age. We investigated whether the development of hyperglycemia would alter the ultrastructure of the corneal epithelium. METHODS Scanning and transmission electron microscopy (SEM and TEM) were

Obesity and pituitary gland volume - a correlation study using three-dimensional magnetic resonance imaging

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Purpose: Obesity has become a major health problem and is associated with endocrine disorders and a disturbed hypothalamic-pituitary axis. The purpose of this study was to correlate pituitary gland volume determined by routine magnetic

Clear cell meningioma of the fourth ventricle.

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Clear cell meningioma (CCM) has been identified and included in the World Health Organization classification of CNS tumors recently. CCMs are histologically characterized by sheets of polygonal cells with clear cytoplasm, which is the expression of high glycogen concentration. Compared with other

Endogenous Cushing's Syndrome with Precocious Puberty in an 8-Year-Old Boy due to a Large Unilateral Adrenal Adenoma.

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Adrenocortical tumors (ACTs) causing Cushing's syndrome are extremely rare in children and adolescents. Bilateral macronodular adrenocortical disease which is a component of the McCune-Albright syndrome is the most common cause of endogenous Cushing's syndrome. We report the case of a boy with

Early atherosclerotic lesions in a susceptible rat model. The LA/N-corpulent rat.

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The LA/N-cp rat, when homozygous for the mutant cp gene, is obese and moderately hyperlipidemic. Body weight of homozygotes reaches approximately 950 g compared to 400 g for lean heterozygotes. In adult animals plasma triglycerides are 330 mg/100 ml compared to 40 mg/100 ml, and total cholesterol is

Establishment and characterization of novel human oral squamous cell carcinoma cell lines from advanced‑stage tumors of buccal mucosa.

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Oral squamous cell carcinoma (OSCC) is a leading cause of mortality in India owing to the high percentage of tobacco chewers, smokers and alcohol consumption. OSCC is highly heterogeneous in nature; therefore poses a challenge in the treatment of the patient. To better understand the heterogeneity

Hepatic differentiation of human amniotic epithelial cells and in vivo therapeutic effect on animal model of cirrhosis.

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OBJECTIVE Human amniotic epithelial cells (hAECs) have been touted as an ideal stem cell candidate, being ethically neutral, immunologically naïve, plentiful in origin, and retaining plasticity in its fetal stage. We hypothesized that by applying natural physiological signals of the developing

Characterization of human gastric adenocarcinoma cell lines established from peritoneal ascites.

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The three cell lines, designated as gastric cancer (GC)1401, GC1415 and GC1436 were derived from peritoneal effusions from patients with gastric adenocarcinoma. Cell lines were established in tissue culture and in immunodeficient, non-obese diabetic/severe combined immunodeficiency (NOD/SCID) mice.
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