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portuguese/inactivation métabolique
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Esters of okadaic acid and dinophysistoxin-2 in Portuguese bivalves related to human poisonings.
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Liquid chromatography (HPLC) was used to search for esters of DSP toxins in Portuguese bivalves. Hexane-soluble derivatives of okadaic acid (OA) and dinophysistoxin-2 (DTX-2) were found. Presumably they are acyl derivatives, globally known as 'dinophysistoxin-3' (DTX-3). In certain instances DTX-3
Geographical variation and partition of metals in tissues of Octopus vulgaris along the Portuguese coast.
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Zinc, Cu, Cd, Pb and Hg were determined in mantle, arm and digestive gland of 59 individuals of Octopus vulgaris captured at six sites along the Portuguese coast. Metal concentrations in tissues did not vary significantly (P<0.05) with size/weight, sex or sexual stage. The abundance of metals in
Oral Health-Related Quality of Life Among a Portuguese Sample of Institutionalised Alcoholic Patients under Rehabilitation Therapy.
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OBJECTIVE
To assess the self-reported Oral Health Related Quality of Life (OHRQoL) among institutionalised patients in an alcoholic detoxification programme in northern Portugal.
METHODS
This analytical cross-sectional study using the Oral Health Impact Profile-49 (OHIP-49) was carried out in 300
Increased frequency of wild-type arylamine-N-acetyltransferase allele NAT2*4 homozygotes in Portuguese patients with colorectal cancer.
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Here we report that colorectal cancer patients show a markedly higher frequency (3-fold) of wild-type NAT2*4 allele homozygotes than the control population. However, a marked difference in NAT2*4/NAT2*4 genotype frequency associated with the patients gender was observed pointing to a male-specific
Bentazon triggers the promotion of oxidative damage in the Portuguese ricefield cyanobacterium Anabaena cylindrica: response of the antioxidant system.
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Rice fields are frequently exposed to environmental contamination by herbicides and cyanobacteria, as primary producers of these aquatic ecosystems, are adversely affected. Anabaena cylindrica is a cyanobacterium with a significantly widespread occurrence in Portuguese rice fields. This strain was
The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.
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Glutathione-S-transferases (GSTs) are a super-family of phase II metabolizing enzymes that catalyse the detoxification of a large range of endogenous and exogenous toxic compounds, playing an important role in protecting cells against damage, through glutathione conjugation with electrophilic
Bioethanol from the Portuguese forest residue Pterospartum tridentatum--an evaluation of pretreatment strategy for enzymatic saccharification and sugars fermentation.
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Under the current energy scenario, the development of alternatives to fossil fuels, like bioethanol from lignocellulosic materials, is highly relevant. Therefore it is important to search and study new raw materials and to optimize the different steps that lead to bioethanol production. In this
Biodegradation of ochratoxin A by fungi isolated from grapes.
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Ochratoxin A is a mycotoxin present in several food products for which levels should be reduced. Chemical, physical, and biological methods have been proposed for the detoxification of mycotoxins, biological methods being the more promising ones. In this report, filamentous fungi isolated from
Differential dynamics of dinophysistoxins and pectenotoxins, part II: offshore bivalve species.
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Different dinophysistoxin's profiles have been found repeatedly amongst some offshore bivalve molluscs. Species such as the clam, Spisula solida, esterify dinophysistoxins to a great extent, and contain always more okadaic acid (OA) than dinophysistoxin-2 (DTX2). In contrast, the clam Donax
Toxic levels of manganese in an acidic Cambisol alters antioxidant enzymes activity, element uptake and subcellular distribution in Triticum aestivum.
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In the Montado system, in Portuguese Alentejo region, some Eutric Cambisols are known to promote manganese (Mn) toxicity in wheat. Variation on bioavailable Mn concentration depends on soil acidity, which can be increased by natural events (e.g. waterlogging) or human activity (e.g. excess use of
Genetic polymorphisms of phase I and phase II metabolic enzymes as modulators of lung cancer susceptibility.
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OBJECTIVE
Tobacco exposure remains the main etiologic factor for lung cancer (LC). Interactions between environment and individual genetic profile are particularly important for this disease. The aim of this study was to evaluate the contribution of CYP1A1*2A, CYP1A1*2C, CYP2D6*4, GSTP1, GSTM1,
Seasonal patterns of polycyclic aromatic hydrocarbons in digestive gland and arm of octopus (Octopus vulgaris) from the Northwest Atlantic.
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Among organic pollutants existing in coastal areas, polycyclic aromatic hydrocarbons (PAHs) are of great concern due to their ubiquity and carcinogenic potential. The aim of this study was to evaluate the seasonal patterns of PAHs in the digestive gland and arm of the common octopus (Octopus
Mercury levels in parturient and newborns from Aveiro region, Portugal.
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Since the outbreak of methylmercury (MeHg) poisoning in Japan and Iraq, mercury (Hg) is classified as well-established teratogen. The Portuguese region of Aveiro faced some decades ago an environmental Hg contamination due to activities from a chlor-alkali plant. Until now, no apparent evaluation
Differential dynamics of dinophysistoxins and pectenotoxins between blue mussel and common cockle: a phenomenon originating from the complex toxin profile of Dinophysis acuta.
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Different toxin profiles of dinophysistoxins and pectenotoxins have been reported before between blue mussel and other bivalve species, such as common cockle, razor clam, clams, etc. Comparison of toxins present in plankton in mussel growing areas and in cockle growing areas, respectively, showed
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