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OBJECTIVE
To develop Portuguese evidence-based recommendations for pain management by pharmocotherapy in inflammatory arthritis.
METHODS
The Portuguese project was integrated in the multinational 3E Initiative (Evidence, Expertise, Exchange) 2010 where a total of 453 rheumatologists from 17
BACKGROUND
Unbiased cluster analysis using clinical parameters has identified asthma phenotypes. Adding inflammatory biomarkers to this analysis provided a better insight into the disease mechanisms. This approach has not yet been applied to asthmatic Portuguese patients.
OBJECTIVE
To identify
Despite aggressive treatment, sarcoidosis may be debilitating and progressive. The role of tumor necrosis factor (TNF)-a in the genesis of granulomas is ambiguous. It has proven to be critical in the formation and maintenance of granulomatous inflammation and its antagonist, Infliximab, has
Objective: Tinnitus is associated with various conditions such as presbycusis, infectious, autoimmune and many other diseases. Our study aims to identify an association between inflammatory markers and the presence of tinnitus or hearing loss (HL).Design: Exploratory study including a
A novel dilated cardiomyopathy (DCM) in 12 related Portuguese Water Dogs was identified by retrospective analysis of postmortem and biopsy case records. Male and female puppies born to clinically healthy parents typically died at 13 (+/- 7.3) weeks of age (range, 2-32 weeks) because of congestive
BACKGROUND
Syphilis is a systemic human disease which is caused by infection with the spirochete Treponema pallidum. It is spread worldwide, and there has recently been an increase in its incidence. Neurosyphilis (NS) can have a variety of presentations; meningovascular NS is a specific affection of
OBJECTIVE
Drug-induced anaphylaxis is an unpredictable and potentially fatal adverse drug reaction. The aim of this study was to identify the causes of drug-induced anaphylaxis in Portugal.
METHODS
During a 4-year period a nationwide notification system for anaphylaxis was implemented, with
A careful history was taken in an attempt to document an unusual delayed inflammatory reaction involving the ears and oral cavity. Severe oral and auricular inflammations have been described as apparent reactions to stings on the patient's foot by a Portuguese man-of-war (P physalia). Toxin was
OBJECTIVE
To characterise the colonoscopies performed in the Portuguese District Hospitals.
METHODS
Transverse study conducted between 7 and 18 March 2005 amongst the 33 District Hospitals throughout Portugal. Data collected included the following: gender, age, geographical origin, ambulatory or
A dog model has been used to evaluate histological changes arising from senescence. Autopsies of 145 Portuguese Water Dogs have been used to evaluate the individual and group "state of health" at time of death. For each dog, weights or dimensions of organs or tissues were obtained, together with
Multiple sclerosis is a chronic inflammatory disease, in which a diagnostic delay could reduce the available therapeutic options. Therefore, it is important to monitor the time to diagnosis and understand factors that may potentially reduce it. The objective of this study was to The concept of spondylarthropathy (SPAP) covers a series of pathologies sharing a common genetic basis and infectious triggers.
OBJECTIVE
To present and discuss the prevalence of SPAP in the Coimbra identified skeletal collection, a 19th-20th century Portuguese sample.
METHODS
Each of the 505
BACKGROUND
Anaemia can be considered the most common extra-intestinal manifestation in inflammatory bowel disease. Nevertheless, anaemia is often under-diagnosed and under-treated both in adults and children with inflammatory bowel disease. Herein, we report the consensus statements on the
BACKGROUND
Asthma is a heterogeneous chronic inflammatory condition characterised by reversible airway obstruction and hyperresponsiveness associated with underlying bronchial inflammation and structural changes. It represents an increasing health problem and is a huge burden on the patients, their
OBJECTIVE
To estimate the prevalence of self-reported drug allergy in adults.
METHODS
Cross-sectional survey of a general adult population from Porto (all of whom were living with children involved in the International Study of Asthma and Allergies in Childhood-phase three), during the year 2002,