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riboflavin/hémorragie
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Large animal evaluation of riboflavin and ultraviolet light-treated whole blood transfusion in a diffuse, nonsurgical bleeding porcine model.
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BACKGROUND
The Mirasol system has been demonstrated to effectively inactivate white blood cells (WBCs) and reduce pathogens in whole blood in vitro. The purpose of this study was to compare the safety and efficacy of Mirasol-treated fresh whole blood (FWB) to untreated FWB in an in vivo model of
Transcriptional profiling of liver in riboflavin-deficient chicken embryos explains impaired lipid utilization, energy depletion, massive hemorrhaging, and delayed feathering.
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A strain of Leghorn chickens (rd/rd), unable to produce a functional riboflavin-binding protein, lays riboflavin-deficient eggs, in which all embryos suddenly die at mid-incubation (days 13-15). This malady, caused by riboflavin deficiency, leads to excessive lipid accumulation in liver, impaired
Ascorbic acid, riboflavin, thiamin, and nicotinic acid in relation to severe injury, hemorrhage, and infection in the human.
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Ascorbic Acid, Riboflavin, Thiamin, and Nicotinic Acid in Relation to Severe Injury, Hemorrhage, and Infection in the Human.
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Towards the understanding of the UV light, riboflavin and additive solution contributions to the in vitro lesions observed in Mirasol®-treated platelets.
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Development of a riboflavin and ultraviolet light-based device to treat whole blood.
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BACKGROUND
In the United States, blood components are commonly used for patients in need of massive transfusion after blood loss. In combat situations, when severe traumatic injuries occur far from a hospital, fresh whole blood is a valuable transfusion therapy because components may not be
Our experience in riboflavin and ultraviolet light pathogen reduction technology for platelets: from platelet production to patient care.
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BACKGROUND
Pathogen reduction technology (PRT) enhances blood component safety, but its implementation is hampered by loss of blood quality and cost.
METHODS
A retrospective study was conducted to investigate the efficacy, safety, and cost of 9673 riboflavin and ultraviolet light-treated platelet
Evaluation of the post-transfusion platelet increment and safety of riboflavin-based pathogen reduction technology (PRT) treated platelet products stored in platelet additive solution for 5 days or less versus 6-7 days.
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OBJECTIVE
Platelets are stored routinely for 5 days or less and extended platelet storage time could improve product availability. This study compared platelet count increments (CI24hs) of riboflavin plus UV-light (PRT) treated platelet products in platelet additive solution stored for 5 days or
Termination of pregnancy in mice with antiserum to chicken riboflavin-carrier protein.
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The importance of riboflavin-carrier protein (RCP) in the maintenance of pregnancy in mice has been studied. Selective passive immunoneutralization of the maternal RCP resulted in fetal death and resorption. Six hours after chicken RCP antiserum treatment, the following observations were made: there
Effects of riboflavin on Gunn rats under phototherapy.
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Blue and white phototherapy was given to infant (and weanling) homozygous Gunn rats treated with different doses of riboflavin-5-phosphate (ribofl.5'p.) During the first hours after a flavin-injection, the effect of phototherapy with both types of fluorescent lamps was enhanced. With equal radiant
Riboflavin attenuates lipopolysaccharide-induced lung injury in rats.
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Riboflavin (vitamin B2) is an easily absorbed micronutrient with a key role in maintaining health in humans and animals. It is the central component of the cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) and is therefore required by all flavoproteins. Riboflavin also
Vitamin profiles of eggs as indicators of nutritional status in the laying hen: riboflavin study.
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Two experiments determined the effect of dietary riboflavin supplementation on egg yolk and albumen riboflavin concentrations, egg production, egg weight, shell thickness, hen weight, hatchability, incidence of clubbed down, and incidence of hemorrhagic embryos. In the first experiment, hens were
Damage threshold in adult rabbit eyes after scleral cross-linking by riboflavin/blue light application.
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Several scleral cross-linking (SXL) methods were suggested to increase the biomechanical stiffness of scleral tissue and therefore, to inhibit axial eye elongation in progressive myopia. In addition to scleral cross-linking and biomechanical effects caused by riboflavin and light irradiation such a
Treatment of Whole Blood With Riboflavin and UV Light: Impact on Malaria Parasite Viability and Whole Blood Storage.
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BACKGROUND
Sub-Saharan African countries utilize whole blood (WB) to treat severe anemia secondary to severe blood loss or malaria on an emergency basis. In many areas with high prevalence of transfusion-transmissible agents, blood safety measures are insufficient. Pathogen reduction technology
Preliminary clinical and anthropometric findings from the first Health and Nutrition Examination Survey, USA, 1971-1972.
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Eight percent of Negroes between the ages of 45 to 59 had hepatomegaly. Tongue signs and absent knee and ankle jerks were more prevalent in Negroes ages 45 to 74; they also had lower urinary excretion of thiamine and riboflavin than Whites. Bowed legs and knock knees were more frequent in Negroes
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