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Glucocorticoid-like effects of antihepatocarcinogen Rotenone are mediated via enhanced serum corticosterone levels: Molecular Fitting and Receptor Activation Studies.
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BACKGROUND: Recent studies suggest that rotenone alters cell signal transduction pathways in a manner similar to glucocorticoids. Histological and biochemical markers of glucocorticoid effects in vivo, evaluated in our laboratories, provide further evidence for similarities in the activity of
Teratogenicity study on pyrethrum and rotenone (natural origin) and ronnel in pregnant rats.
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Insecticidal formulations in the form of dusts or aerosols containing rotenone from the root of Derris elliptica and pyrethrum from the flower of Chrysanthemum cinerariaefolium are commonly used in homes and gardens. Ronnel (fenchlorphos), a systemic insecticide, is used to control house flies and,
Submitochondrial location and electron transport characteristics of enzymes involved in proline oxidation.
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Isolated corn mitochondria (Zea mays cv. B73 x Mo17) were fractionated and the fragments were separated on a 20-45% (weight/weight) continuous sucrose gradient. Soluble enzymes remained at the top of the gradient overlapping with the outer membranes, while inner membrane vesicles and intact inner
[The effect of dietary Omega 6 polyunsaturated fatty acids on the activity of enzymes associated with liver mitochondrial and placental function in rats].
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Female virgin rats, Wistar strain, divided into three groups of 18 each, were fed either a diet containing 45% of calories as fat (45 g%), the second received low-fat diet (15 g%), before and throughout pregnancy, and the third served as control. For both dietary fat levels, the polyunsaturated to
Analysis of donors of electrons to photosystem I and cyclic electron flow by redox kinetics of P700 in chloroplasts of isolated bundle sheath strands of maize.
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Bundle sheath chloroplasts of NADP-malic enzyme (NADP-ME) type C4 species have a high demand for ATP, while being deficient in linear electron flow and oxidation of water by photosystem II (PSII). To evaluate electron donors to photosystem I (PSI) and possible pathways of cyclic electron flow (CEF1)
Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice.
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Deguelin [(7aS,BaS)-13,13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-Bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one], a naturally occurring rotenone, has shown chemopreventive efficacy in several in vivo and in vitro models. In this report, the effectiveness of deguelin at inhibiting the development
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