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theophylline/accident vasculaire cérébral
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Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.
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BACKGROUND
Theophylline causes potent cerebral vasoconstriction which decreases blood flow in the non-ischaemic areas of the brain and increases collateral blood flow surrounding the ischaemic region.
OBJECTIVE
The objective of this review was to assess the effect of theophylline and its analogues
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.
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BACKGROUND
Theophylline causes potent cerebral vasoconstriction which decreases blood flow in the non-ischaemic areas of the brain and increases collateral blood flow surrounding the ischaemic region. NOTE: This review covers an area where no active research is taking place. It will be updated if
Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial
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Background and purpose: Delayed recanalization increases the risk of infarct growth and poor clinical outcome in acute ischemic stroke. The vasoactive agent theophylline has shown neuroprotective effects in animal stroke models but
Theophylline as an add-on to thrombolytic therapy in acute ischaemic stroke (TEA-Stroke): A randomized, double-blinded, placebo-controlled, two-centre phase II study.
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The neurophysiological effects of single-dose theophylline in patients with chronic stroke: A double-blind, placebo-controlled, randomized cross-over study.
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Reducing inhibitory neurotransmission with pharmacological agents is a potential approach for augmenting plasticity after stroke. Previous work in healthy subjects showed diminished intracortical inhibition after administration of theophylline.
We assessed the effect of single-dose theophylline on
[Treatment of apoplexy with a theophylline derivative & ephedrine in the light of recent pathogenetic theories].
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[ON THE TREATMENT OF APOPLEXY WITH COMPLAMIN (7-(2-HYDROXY-3-(N-2-HYDROXYETHYL-N-METHYLAMINO)PROPYL)THEOPHYLLINE NICOTINATE].
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[Effect of combined theophylline-ethylenediamine, rutin and ascorbic acid in therapy of cerebral apoplexy; early clinico-therapeutic results].
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Lack of effect of theophylline on the outcome of acute cerebral infarction.
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In patients with acute ischemic stroke, dramatic but often transient improvements have been noticed after theophylline injections. Whether better results could be obtained by continuous infusion of the drug was evaluated in a double-blind study. Out of 46 patients with a mean age of 75 years, 22 got
Cardiovascular effects of toxic concentrations of theophylline in the dog.
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A canine model of theophylline toxicity was used to study the cardiovascular effects seen in severe theophylline poisoning. Eight mongrel dogs were divided equally into two groups. The dogs were anesthetized with pentobarbital and paralyzed with pancuronium bromide. They were ventilated with 100%
Left ventricular function in asthmatic children chronically treated with theophylline evaluated by exercise Doppler echocardiography.
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To evaluate the chronic effects of theophylline on cardiac function, M-mode and pulsed Doppler derived variables were measured at rest and the suprasternal continuous wave Doppler measurement of ascending aortic flow was used during treadmill exercise testing. Subjects consisted of 13 children with
Cardiac output changes secondary to theophylline therapy in preterm infants.
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The cardiovascular effects of theophylline were studied in 11 clinically stable preterm infants. Theophylline was given as aminophylline using a loading dose of 6.8 mg/kg and a maintenance dose of 2 mg/kg every 8 hours intravenously. Cardiac output, stroke volume, and heart rate were measured using
Cardiovascular response to increasing theophylline concentrations.
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The circulatory effects of plateau plasma theophylline concentrations of 5, 10 and 20 mg/l were examined in normal male volunteers using forearm plethysmography, systolic time intervals and echocardiography. Systemic arterial and forearm venous pressures were not significantly altered during
Comparison of once-a-day and twice-a-day theophylline in asthma.
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Sustained-release theophylline compounds given once (Uniphyl) or twice (Theodur) daily were compared in adult asthmatics. Following a single dose of oral medication, large and peripheral airways bronchodilation occurred; response to theophylline correlated significantly with the log plasma
[Acute theophylline intoxication as differential diagnosis of pneumothorax in an asthma patient].
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The ambulance was called to a known asthmatic patient. On arrival, the team found a massively dyspnoeic, diaphoretic, non-cyanotic and somnolent patient. His medication consisted of oral theophylline (unknown dosage), fenoterol (metered-dose inhaler), as well as 8 mg oral prednisolone. On the day of
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