group of patients will do F-18FDG PET/CT scan after negative whole body scan with elevated serum thyroglobulin Antibody or Thyroglobulin levels.

Thyroid Cancer

Thyroid Cancer and (FDG)PET/CT Scan

Role of of F-18-fluoro-deoxy-glucose (FDG) PET/CT in Thyroid Cancer Patients With Negative I-131whole Body Scan and Elevated Thyroglobulin Level or Positive Anti Thyroglobulin Antibodies

Detection of recurrence or metastasis in patient with negative radioactive iodine scan and elevated stimulated thyroglobulin (sTg) or thyroglobulin antibody (TgAb) levels.By progressively increase level of serum Thyroglobulin or thyroglobulin antibodies

initiate appropriate treatment to those patients improve survival and quality of life

RMFarghali

Principal investigator

Assiut University

Patients with slightly decreased BMD (T or Z-score in lumbar spine or neck region of femur > -2.0 SD by dual energy X-ray) taking suppressive doses of L-T4 to treatment divided into 2 groups of 99Tc-MDP (Technetium [99Tc] methylenediphosphonate) and calcium alone.99Tc-MDP group:10mg Intravenous drip every 1week for ten weeks, every 2weeks for 22 weeks, every 1 month for 4 months.

600mg caltrate containing vitamin D everyday for 12 months.

148 patients with obviously decreased BMD (T or Z-score in lumbar spine or neck region of femur≤-2.0 SD) taking suppressive doses of L-T4 divided into 2 groups of 99Tc-MDP and or fosamax. 99Tc-MDP group:15mg 99Tc-MDP Intravenous drip every 1week for ten weeks, every 2weeks for 22 weeks, every 1 month for 4 months (99Tc-MDP) for 12 months.

Differentiated Thyroid Cancer

Osteoporosis

99Tc-MDP

fosamax

Caltrate

Nuclear Medicine Xinhua Hospital

99Tc-MDP in Postmenopausal Women With Differentiated Thyroid Cancer and Decreased Bone Mineral Density

Prospective Trial of 99Tc-MDP and Alendronate Sodium in Postmenopausal Women With Differentiated Thyroid Cancer and Decrease in Bone Mineral Density Treated With Supraphysiological Doses of Thyroid Hormone

The changes of T score in lumbar and hip by dual energy x-ray absorptiometry

bone turnover markers including osteocalcin, C-telopeptides of type I collagen (CTX), Type I N-procollagen terminal propeptide

On numerical rating scale of 0 to 10 where 0 is no pain and 10 is the worst pain.

health-related quality of life questionnaire by Short Form-36 (SF-36) scores including physical health (physical functioning; physical role; bodily pain; general health) ;Mental health (vitality; social functioning; emotional role; mental health).Minimum score 0,maximum score, scores above 50 are better than the general population average for all scales, while scores below 50 are worse.

A transient rash and phlebitis, gastrointestinal reaction.

Chao Ma

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

patients with positive slope in the levels of free serum calcium levels between 6th and 12th postoperative hour

patients with negative or no slope in the levels of free serum calcium levels between 6th and 12th postoperative hour.

Hypocalcemia After Total Thyroidectomy

G.Hatzikosta General Hospital

The Study of a Safe and Cost-effective Method to Identify Patients at Low Risk of Significant Hypocalcemia After Total Thyroidectomy.

The Study of a Safe and Cost-effective Method to Identify Patients at Low Risk for the Development of Significant Hypocalcemia After Total Thyroidectomy.

thyroid neoplasms/phosphatase

Thyroid Cancer and (FDG)PET/CT Scan

99Tc-MDP in Postmenopausal Women With Differentiated Thyroid Cancer and Decreased Bone Mineral Density

The Study of a Safe and Cost-effective Method to Identify Patients at Low Risk of Significant Hypocalcemia After Total Thyroidectomy.

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