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15 résultats
Discovery for Biomarkers and Risk Factors for Postoperative Delirium in Elderly Patients With Spine Surgery
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Method:
1. Study design: This study is a prospective investigation that identifies risk factors for postoperative delirium and searches for predictive biomarkers of delirium.
2. Inclusion criteria / Exclusion Criteria
1. Inclusion criteria
- Elderly patients over 70
- Eligible Surgeries: lumbar
Intraoperative Molecular Diagnosis of Sentinel Lymph Node In Breast Cancer Patients
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Patients:
More than 1000 consecutive breast cancer patients scheduled for Sentinel Lymph Node Biopsy (SLNB) were enrolled in the study. The study was approved by the ethics committee of each center and each patient provided informed consent. The patients who had undergone previous ipsilateral
Multiparametric Magnetic Resonance Imaging Versus Fine Needle Aspiration Cytology for Parotid Gland Neoplasms
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Participants affected by parotid gland neoplasms are evaluated by an ear, nose and throat surgeon in our hospital, who defines the indication to surgical removal.
Preoperative management includes:
- Clinical Evaluation: participant's history and physical examination are collected. Participants are
Perfusion Assessment With Contrast-Enhanced EUS in Locally Advanced and Metastatic Pancreatic Cancer
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Introduction and rationale:
Pancreatic cancer (PC) is one of the most lethal and therapeutically resistant malignancies, with a grim prognosis that is attributed to the late clinical presentation and the relative chemoresistance of the disease.
Even with identical chemotherapy regimens, some
Contrast-Enhanced Ultrasound in Diagnosing Patients With Liver Cancer Undergoing Yttrium-90 Radioembolization
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PRIMARY OBJECTIVES:
I. Investigate the relationship between hepatocellular carcinoma (HCC) tumor perfusion on pre-procedural contrast-enhanced ultrasound (CEUS) time intensity curve (TIC) and post-procedural Yttrium-90 (90Y) microsphere distribution after 90Y radioembolization (RE).
SECONDARY
Social Navigation for Adolescents in ED
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Significant advances have been made in pediatrics in the United States in the last 60 years. Mortality from infectious disease and cancer, for instance, has declined significantly. The more stubborn issues in pediatrics include poor asthma control, obesity, suicide and adolescent homicide. To
A New Clinic-Genetic Risk Score for Predicting Venous Thromboembolic Events in Cancer Patient
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The working hypothesis of this study establishes that the risk of cancer patients suffering a thromboembolic event is conditioned by individual genomic factors. The genes to be analyzed have clearly demonstrated their relationship with thromboembolic disease in other clinical contexts. This study is
Doxorubicin-associated Cardiac Remodeling Followed by CMR in Breast Cancer Patients
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This prospective cohort study was performed at the State University of Campinas, Brazil. The Institutional Review Board of the State University of Campinas approved the study and all participants provided informed consent. Female patients with breast cancer who received anthracycline (doxorubicin or
Clinical Impact of EUS Elastography Mean Strain Histograms (SH) and Contrast Peak-enhancement in Focal Pancreatic Masses and Lymph Nodes
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1. Background Endoscopic ultrasound (EUS) is a technique with a major clinical impact in digestive diseases, determining a change in the diagnosis and management of more than half of examined patients [1]. Recent advances in EUS-FNA techniques, but also the development of real-time EUS elastography
Prostate Hypoxia - TIC
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Chloroquine With Taxane Chemotherapy for Advanced or Metastatic Breast Cancer After Anthracycline Failure (CAT)
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The purpose of this study is to determine the anti-tumor activity of the combination of Chloroquine combined with a Taxane or Taxane-like chemo agents(Paclitaxel, Docetaxel, Abraxane, Ixabepilone).
The laboratories have developed robust preclinical models utilizing both in vitro systems such as the
Pilot Study of the Modified Atkins Diet for Tourette Syndrome
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Metformin in Amnestic Mild Cognitive Impairment
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The prevalence of Alzheimer's disease (AD) is expected to quadruple by the year 2047. There are no known curative or preventive measures for AD. Current treatment options for AD only address symptoms, and no treatments are available that focus on delaying the actual disease process. One of the
Neurological Outcome With Carotid Artery Stenting
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We hypothesize that the incidence of subtle neuropsychometric injury will be significantly greater than the incidence of stroke comparable to what we found in patients having carotid endarterectomy. Patients will be evaluated prospectively to determine the incidence of neurological morbidity based
Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid Tumors
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All of the chemotherapy drugs used in this study are FDA approved and commercially available drugs designed to kill cancer cells.
Before you can start treatment on this study, you will have what are called "screening tests". These tests will help the doctor decide if you are eligible to take part in
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