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Chin tremor in full-term neonate after hypoxia.
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BACKGROUND
Newborns may present a range of motor phenomena that are not epileptic in nature. Chin tremor is an unusual movement disorder that typically starts in early childhood and may be precipitated by stress and emotion. Its pathophysiology has not been fully elucidated.
METHODS
We describe a
Effects of acute hypoxia on postural and kinetic tremor.
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Human physiological tremor is a complex phenomenon that is modulated by numerous mechanical, neurophysiological, and environmental conditions. Researchers investigating tremor have suggested that acute hypoxia increases tremor amplitude. Based on the results of prior studies, we hypothesized that
Acute hypoxia activates human 8-12 Hz physiological tremor.
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Hypoxia causes arousal. Therefore, we hypothesized that hypoxia activates the human somatomotor system and should augment tremor. We determined the effects of hypoxia, PET(O2) = 45+/-2.2 mm Hg, hypocapnia, and the hypocapnic-hypoxic interaction on finger tremor during elastic loading. A total of 12
Inhalation of the nerve gas sarin impairs ventilatory responses to hypercapnia and hypoxia in rats.
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Sarin, a highly toxic nerve gas, is believed to cause bronchoconstriction and even death primarily through respiratory failure; however, the mechanism underlying the respiratory failure is not fully understood. The goals of this study were to ascertain whether sarin affects baseline ventilation (VE)
The effects of hypoxia on the metabolic and cardiorespiratory responses to shivering produced by external and central cooling in the pigeon.
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Respiratory, cardiovascular and blood gas responses of pigeons to spinal cord cooling (36 +/- 1 degrees C), to ambient cooling (Ta = 5 degrees C) and to simultaneous spinal cord and ambient cooling were measured at three different levels of fractional inspired oxygen concentration (FIO2 = 0.209,
Postural stability during slow-onset and rapid-onset hypoxia.
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The standing steadiness and postural tremor of seven male volunteers were examined during slow and rapid induction of hypoxia. Spectrum analysis of position coordinates and tremor data generated from a quartz multicomponent force measuring platform and a tremor transducer showed that postural tremor
The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans.
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Hypoxemia can be life-threatening, both acutely and chronically. Because hypoxemia causes vascular dysregulation that further restricts oxygen availability to tissue, it can be pharmacologically addressed. We hypothesized that theophylline can be safely combined with the β2-adrenergic vasodilator
Primary writing tremor: a selective action tremor.
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Progressive difficulty in handwriting due to jerking movements precipitated by the act of writing beginning between the ages of 8 to 54 is reported in six patients. There was no rest tremor, but three had mild postural tremor. Specific muscle activity (especially pronation of the wrist or abduction
Comparison of DuP 996, with physostigmine, THA and 3,4-DAP on hypoxia-induced amnesia in rats.
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DuP 996, 3,3-bis(4-pyrindinylmethyl)-1-phenylindolin-2-one, physostigmine (PH), tetrahydroaminoacridine (THA) and 3,4-diaminopyridine (3,4-DAP) were compared for their ability to protect against hypoxia-induced performance deficits in a passive avoidance (PA) task. The ability to retain PA response
Spontaneous post-anesthetic tremor does not resemble thermoregulatory shivering.
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Spontaneous post-anesthetic tremor that resembles shivering is common during recovery from anesthesia. Risks to postoperative patients include an increase in metabolic rate of up to 400%, hypoxemia, wound dehiscence, dental damage, and disruption of delicate surgical repairs. The etiology of
Intermittent hypoxia conditioning prevents behavioral deficit and brain oxidative stress in ethanol-withdrawn rats.
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Intermittent hypoxia (IH) has been found to protect brain from ischemic injury. We investigated whether IH mitigates brain oxidative stress and behavioral deficits in rats subjected to ethanol intoxication and abrupt ethanol withdrawal (EW). The effects of IH on overt EW behavioral signs, superoxide
[Thermoregulatory activity of the motor neuron pool in the rat adapted to cold and hypoxia].
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The impulse activity of single motor units were investigated in anesthetized rats during cold tremor. Cold adaptation resulted in a decrease whereas hypoxic adaptation evoked an increase of the firing rate of the motor units during cold tremor.
Proteolipid protein gene mutation induces altered ventilatory response to hypoxia in the myelin-deficient rat.
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Pelizaeus Merzbacher disease is an X-linked dysmyelinating disorder of the CNS, resulting from mutations in the proteolipid protein (PLP) gene. An animal model for this disorder, the myelin-deficient (MD) rat, carries a point mutation in the PLP gene and exhibits a phenotype similar to the fatal,
The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
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Parkinson's disease (PD) is a progressive, chronic disease characterized by dyskinesia, rigidity, instability, and tremors. The disease is defined by the presence of Lewy bodies, which primarily consist of aggregated α-synuclein protein, and is accompanied by the loss of monoaminergic neurons.
The pharmacological effects of the anesthetic alfaxalone after intramuscular administration to dogs.
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The pharmacological effects of the anesthetic alfaxalone were evaluated after intramuscular (IM) administration to 6 healthy beagle dogs. The dogs received three IM doses each of alfaxalone at increasing dose rates of 5 mg/kg (IM5), 7.5 mg/kg (IM7.5) and 10 mg/kg (IM10) every other day. Anesthetic
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