Consecutive early stage breast cancer patients who are treated according to the national guidelines. Observation over 11 years.

Breast Cancer

Breast Cancer is 100 x more frequent in female than in male

Breast Concervative or Meastectomy

Helse Stavanger HF

Helse Bergen HF

Prospective Breast Cancer Biobanking

Prospective Breast Cancer Biobanking Project

Time from surgery to relapse of breast cancer

Time from surgery until death of any cause

VAS=visual analogue scale; range 0 to 100 mm; higher score is worse fatigue)

percent of patients on disability pension i.e not participation in work

The precent of patients still on tamoxifen after 5 years and 10 years follow-up

The precent of patients still on taromatase inhibitor after 2 years and 5 years follow-up

Percent infiltration of inflammation cells (higer score means more inflammation)

Haavard Soiland

Consultant Breast Cancer Surgery / Professor dr. med.

Helse-Bergen HF

Hispanic and NHW women undergoing either a benign breast surgery or prophylactic mastectomy.

Hispanic and NHW with newly diagnosed TNBC. Patients with TNBC will be eligible regardless of whether their treatment plan is surgery first or chemotherapy first (neoadjuvant chemotherapy).

Four (4) 16-gauge core needle biopsies of breast tissue. Ten (10) ml of blood

Triple Negative Breast Cancer

Blood draws will be done in OR by research staff. Tissue will be obtained at the time of their definitive surgery or at the time of port placement. For women going to surgery first, four (4) 16-gauge core needle biopsies will be obtained by research staff after the tumor has been removed from the patient and the specimen is on the collection table in the OR.
For women who are getting neo-adjuvant therapy prior to surgery, the core needle biopsies will be collected at the time of port placement in the OR. The patient will be under light anesthesia for the port placement. Per standard care, we will also use local anesthetic for the needle core biopsy. Port placement requires ultrasound (US). We will take advantage of the US already available in the OR to guide the core needle biopsy. Within 30 minutes of procurement, the tissue from the biopsies will be flash frozen in liquid nitrogen by staff and taken to the lab.

Needle core biopsy

University of Arizona Cancer Center

Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women

Epigenetics of Triple-Negative Breast Cancer in Overweight and Obese Hispanic and Non-Hispanic White Women

DXA studies will be completed prior to surgery or port placement. Blood draws will be done in OR by research staff. Tissue will be obtained at the time of their definitive surgery or at the time of port placement. For women going to surgery first, four (4) 16-gauge core needle biopsies will be obtained by research staff after the tumor has been removed from the patient and the specimen is on the collection table in the OR.
For women who are getting neo-adjuvant therapy prior to surgery, the core needle biopsies will be collected at the time of port placement in the OR.

triple negative breast neoplasms/obésité

Prospective Breast Cancer Biobanking

Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women

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