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Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease
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1. INTRODUCTION
The present invention relates to novel compounds capable of modulating and/or regulating tyrosine kinase signal transduction. The Applicants have demonstrated that the murine fetal liver kinase 1 (FLK-1) receptor and its non-murine counterparts, including the human Kinase
Compounds for the treament of disorders related to vasculogenesis and/or angiogenesis
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1. INTRODUCTION
The present invention relates to novel compounds capable of modulating and/or regulating tyrosine kinase signal transduction. The Applicants have demonstrated that the murine fetal liver kinase 1 (FLK-1) receptor and its non-murine counterparts, including the human Kinase
Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis
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1. INTRODUCTION
The present invention relates to novel compounds capable of modulating and/or regulating tyrosine kinase signal transduction. The Applicants have demonstrated that the murine fetal liver kinase 1 (FLK-1) receptor and its non-murine counterparts, including the human Kinase
Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis
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1. Introduction
The present invention relates to novel compounds capable of modulating and/or regulating tyrosine kinase signal transduction. The Applicants have demonstrated that the murine fetal liver kinase 1 (FLK-1) receptor and its non-murine counterparts, including the human Kinase
Quinazoline compounds and compositions thereof for the treatment of disease
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1. INTRODUCTION
The present invention relates to novel compounds capable of modulating and/or regulating tyrosine kinase signal transduction. The Applicants have demonstrated that the murine fetal liver kinase 1 (FLK-1) receptor and its non-murine counterparts, including the human Kinase
Methods and compositions targeting viral and cellular ITAM motifs, and use of same in identifying compounds with therapeutic activity
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FIELD OF INVENTION
This invention provides methods of treating, reducing the incidence of, and inhibiting metastasis formation of carcinomas, sarcomas, Epstein-Barr virus-induced malignancies, B cell proliferative disorders, and mast cell activation disorders, comprising administering to a subject a
Method of producing hepatocycte growth factor/scatter factor and related cell lines
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BACKGROUND OF THE INVENTION
Hepatocyte growth factor (HGF) was first purified from human and rabbit plasma and rat platelets on the basis of its ability to stimulate mitogenesis of rat hepatocytes. (E. Gohda et al., J. Clin. Invest 81: 414 (1988); R. Zarnegar and G. Michalopoulos, Cancer Res. 49:
Class of arylamide compounds useful as inhibitors of c-fms kinase
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CROSS-REFERENCE TO RELATED APPLICATIONS
Not applicable.
BACKGROUND OP THE INVENTION
1. Field of the Invention
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel arylamide and hetereoarylamide compounds that
Inhibitors of c-fms kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Inhibitors of c-fms kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Inhibitors of c-fms kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Inhibitors of c-fms kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Inhibitors of C-FMS kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Inhibitors of c-fms kinase
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BACKGROUND OF THE INVENTION
The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase.
Protein kinases are enzymes that serve as key components of signal
Inhibitors of C-FMS kinase
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jul. 23, 2013, is named PRD2659USDIV3_SL.txt and is 825 bytes in size.
BACKGROUND OF THE
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