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uremia/triacylglycerol
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Increased serum triacylglycerol and cholesterol binding reserve in acute uremic rats.
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In acute uremic rats (24 h after bilateral nephrectomy, serum urea 280-300 mg/dl) the interface tension of the serum is significantly reduced. Serum levels of triacylglycerol are significantly elevated in uremia, whereas cholesterol levels do not show a significant alteration. The in vitro serum
Triacylglycerol secretion and fatty acid synthesis by the liver in acute uremic rats.
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In bilaterally nephrectomized rats fatty acid synthesis (incorporation of 3H from 3H2O into fatty acids by the liver) and triacylglycerol (TG) secretion by the liver (Triton method) were investigated 24 h after surgery. Starved and fed rats were employed. In uremic rats fatty acid synthesis occurs
Decreased plasma lecithin:cholesterol acyltransfer and associated changes in plasma and red cell lipids in uraemia.
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Plasma lipids, lecithin:cholesterol acyltransferase (LCAT) activity and erythrocyte lipid composition were compared for a group of newly diagnosed uraemic patients and a group of healthy subjects. Plasma triacylglycerol was increased and both total and high-density lipoprotein (HDL) cholesterol were
Metabolite profiling identifies markers of uremia.
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ESRD is a state of small-molecule disarray. We applied liquid chromatography/tandem mass spectrometry-based metabolite profiling to survey>350 small molecules in 44 fasting subjects with ESRD, before and after hemodialysis, and in 10 age-matched, at-risk fasting control subjects. At baseline,
Long term hemodialysis aggravates lipolytic activity reduction and very low density, low density lipoproteins composition in chronic renal failure patients.
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BACKGROUND
Dyslipidemia, particularly hypertriglyceridemia is common in uremia, and represents an independent risk factor for atherosclerosis.
METHODS
To investigate the effects of hemodialysis (HD) duration on very low density lipoprotein (VLDL) and low density lipoprotein (LDL) compositions and
Increased HDL Size and Enhanced Apo A-I Catabolic Rates Are Associated With Doxorubicin-Induced Proteinuria in New Zealand White Rabbits.
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The catabolism and structure of high-density lipoproteins (HDL) may be the determining factor of their atheroprotective properties. To better understand the role of the kidney in HDL catabolism, here we characterized HDL subclasses and the catabolic rates of apo A-I in a rabbit model of proteinuria.
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