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Metabolic perturbations in Welsh Ponies with insulin dysregulation, obesity, and laminitis.
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BACKGROUND
Metabolomics, the study of small-molecule metabolites, has increased understanding of human metabolic diseases, but has not been used to study equine metabolic syndrome (EMS).
OBJECTIVE
(1) To examine the serum metabolome of Welsh Ponies with and without insulin dysregulation before and
Aqueous and ethanolic extracts of welsh onion, Allium fistulosum, attenuate high-fat diet-induced obesity.
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BACKGROUND
Allium fistulosum (Welsh onion) is a traditional medicinal plant used for the treatment of colds, influenza, abdominal pain, headache, and heart disease. This study evaluated the effects of A. fistulosum ethanolic extract (AFE) and aqueous extract (AFW) on body weight and other
Secular trends in established and novel cardiovascular risk factors in Welsh 12-13 year olds: a comparison between 2002 and 2007.
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BACKGROUND
This study examines CVD risk factors trends in Welsh adolescents between 2002 and 2007.
METHODS
CVD risk factor data was examined from two cross-sectional studies. The first study (73 participants; aged 12.9 ± 0.3 years) was completed in 2002. The second study (90 participants; aged 12.9
Ultrasonographic measures of body fatness and their relationship with plasma levels and adipose tissue expression of four adipokines in Welsh pony mares.
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Obesity is responsible for metabolic dysregulations that alter fertility and induce pathologies. The objectives of the present study were to validate a reliable method for the evaluation of body fatness in mares and to associate the body fat estimation data to metabolic changes, including adipokines
The production and distribution of IL-6 and TNF-a in subcutaneous adipose tissue and their correlation with serum concentrations in Welsh ponies with equine metabolic syndrome.
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A main symptom of equine metabolic syndrome (EMS) in ponies is pathological obesity characterized by abnormal accumulation of fat deposits and inflammation. In this study, we analyzed the expression of two pro-inflammatory cytokines, interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), in
Future trends in social inequalities in obesity in England, Wales and Scotland.
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Neuroticism Mediates the Relationship Between Industrial History and Modern-Day Regional Obesity Levels
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Objective: The historical factors and contemporary mechanisms underlying geographical inequalities in obesity levels remain uncertain. In this study we examine whether modern regional variation in obesity is partly a result of the impact
Can self-reported data accurately describe the prevalence of overweight?
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Overweight is an important public health problem affecting around 50% of the population of Wales, resulting in increased risk of illness, premature disability and premature death. The aim of this study was to examine critically the accuracy of self-reported data in describing the prevalence of
Morbid obesity in the UK: A modelling projection study to 2035.
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BACKGROUND
Morbid obesity (body mass index ⩾40 kg/m2) carries a higher risk of non-communicable disease and is associated with more complex health issues and challenges than obesity body mass index ≥30kg/m2 and <40kg/m2, resulting in much higher financial implications for health systems. Although
Prediction of incipient pasture-associated laminitis from hyperinsulinaemia, hyperleptinaemia and generalised and localised obesity in a cohort of ponies.
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BACKGROUND
The ability to predict ponies at increased risk of laminitic episodes, when exposed to nutrient dense pasture, would facilitate management to avoid disease.
OBJECTIVE
To identify variables and clinically useful cut-off values with reproducible diagnostic accuracy for the prediction of
Prevalence of and risk factors for equine obesity in Great Britain based on owner-reported body condition scores.
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BACKGROUND
Few data are available on the prevalence of obesity in the general equine population of Great Britain (GB), and its associated risk factors.
OBJECTIVE
To estimate the prevalence of owner-reported obesity in veterinary-registered horses and ponies in GB, and identify factors associated
The Equine Gastrointestinal Microbiome: Impacts of Age and Obesity.
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Gastrointestinal microbial communities are increasingly being implicated in host susceptibilities to nutritional/metabolic diseases; such conditions are more prevalent in obese and/or older horses. This controlled study evaluated associations between host-phenotype and the fecal microbiome /
ROC generated thresholds for field-assessed aerobic fitness related to body size and cardiometabolic risk in schoolchildren.
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OBJECTIVE
1. to investigate whether 20 m multi-stage shuttle run performance (20mSRT), an indirect measure of aerobic fitness, could discriminate between healthy and overweight status in 9-10.9 yr old schoolchildren using Receiver Operating Characteristic (ROC) analysis; 2. Investigate if
Effects of season and body condition on appetite, body mass and body composition in ad libitum fed pony mares.
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Changes in appetite, body mass (BM), body condition score (BCS), direct (ultrasonographic) and indirect (deuterium oxide dilution technique) measures of body fat were monitored in Welsh Mountain pony mares (n=11, 5-19 years of age) offered ad libitum access to a complete diet (gross energy 16.9±0.07
Exploring the health risks of help-seeking military veterans living in different parts of the UK.
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BACKGROUND
Little is known about the mental and physical health differences of treatment-seeking military veterans across the different nations that make up the UK. The aim of this research was to explore potential health differences in order to support better service planning.
METHODS
A random
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